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C1276

Sigma-Aldrich

L-Cysteine hydrochloride

≥98% (TLC), suitable for UHPLC

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Synonym(s):
(2R)-2-Amino-3-sulfanylpropanoic acid hydrochloride
Linear Formula:
HSCH2CH(NH2)COOH · HCl
CAS Number:
52-89-1
Molecular Weight:
157.62
Beilstein:
3560277
EC Number:
200-157-7
MDL number:
MFCD00064553
UNSPSC Code:
12352209
PubChem Substance ID:
24892395
NACRES:
NA.32

grade

anhydrous

Quality Level

200

Assay

≥98% (TLC)

form

powder

technique(s)

UHPLC: suitable

color

white

mp

174.1-174.7 °C

solubility

H2O: 50 mg/mL, clear, colorless

SMILES string

Cl[H].N[C@@H](CS)C(O)=O

InChI

1S/C3H7NO2S.ClH/c4-2(1-7)3(5)6;/h2,7H,1,4H2,(H,5,6);1H/t2-;/m0./s1

InChI key

IFQSXNOEEPCSLW-DKWTVANSSA-N

Gene Information

human ... AMPA 1(2890) , GRIA2(2891) , GRIA3(2892) , GRIA4(2893) , GRIN1(2902) , GRIN2A(2903) , GRIN2B(2904) , GRIN2C(2905) , GRIN2D(2906) , GRIN3A(116443) , GRIN3B(116444) , GRINA(2907)
mouse ... AMPA 1(14799) , GRIA2(14800) , GRIA3(53623) , GRIA4(14802) , GRIN1(14810) , GRIN2A(14811) , GRIN2B(14812) , GRIN2C(14813) , GRIN2D(14814) , GRIN3A(242443) , GRIN3B(170483) , GRINA(66168)
rat ... AMPA 1(50592) , GRIA2(29627) , GRIA3(29628) , GRIA4(29629) , GRIN1(24408) , GRIN2A(24409) , GRIN2B(24410) , GRIN2C(24411) , GRIN2D(24412) , GRIN3A(191573) , GRIN3B(170796) , GRINA(266668)

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Application

L-Cysteine hydrochloride has been used as a supplement in media to study the metabolic and sleep phenotypes of Drosophila melanogaster. It has also been used as one of the reagents for cell dissociation and single cell collection.

Biochem/physiol Actions

Cysteine (Cys) is a functional sulfur-containing aminoacid that regulates metabolism for growth, reproduction and immunity. It provides the disulfide linkage in proteins and is involved in the transport of sulfur. Cysteine is involved in the formation of hydrogen sulfide that functions as a signaling molecule. Cys residues are present at the catalytic sites of various enzymes.
NMDA glutamatergic receptor agonist that is also an agonist at AMPA glutamatergic receptors at high concentrations.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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