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C6445

Sigma-Aldrich

Sodium cholate hydrate

BioXtra, ≥99%

Synonym(s):

3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt, Cholalic acid sodium salt

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1 G
CN¥323.61
5 G
CN¥691.61
25 G
CN¥3,271.09

CN¥323.61

Available to ship onApril 07, 2025Details

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1 G
CN¥323.61
5 G
CN¥691.61
25 G
CN¥3,271.09

About This Item

Empirical Formula (Hill Notation):
C24H39NaO5 · xH2O
CAS Number:
206986-87-0
Molecular Weight:
430.55 (anhydrous basis)
Beilstein:
3582354
EC Number:
206-643-5
MDL number:
MFCD00150749
UNSPSC Code:
12161900
PubChem Substance ID:
24892867
NACRES:
NA.25

CN¥323.61

Available to ship onApril 07, 2025Details

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description

anionic

product line

BioXtra

Assay

≥99%

form

powder

mol wt

micellar avg mol wt 900-1300

aggregation number

2-3

impurities

≤0.05% Phosphorus (P)
≤0.1% Insoluble matter

CMC

9-15 mM (20-25°C)

solubility

H2O: 1 M, clear, faintly yellow to yellow

anion traces

sulfate (SO42-): ≤0.05%

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1 of 4

This Item
CMC0001CMC0004CMC0007
CONTROLLER SIG10化学感受态细胞 for controlled protein expression

CMC0023

CONTROLLER SIG10化学感受态细胞

SIG10 化学感受态细胞 for protein expression and DNA plasmid production

CMC0001

SIG10 化学感受态细胞

SIG10 MAX Electrocompetent Cells for general cloning & library production

CMC0004

SIG10 MAX Electrocompetent Cells

SIG10 5a化学感受态细胞 for DNA plasmid production

CMC0007

SIG10 5a化学感受态细胞

growth mode

adherent or suspension

growth mode

adherent or suspension

growth mode

adherent or suspension

growth mode

adherent or suspension

biological source

Escherichia coli

biological source

Escherichia coli

biological source

Escherichia coli

biological source

Escherichia coli

morphology

rod shaped

morphology

rod shaped

morphology

rod shaped

morphology

rod shaped

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

storage temp.

−70°C

storage temp.

−70°C

storage temp.

−70°C

storage temp.

−70°C

General description

Sodium cholate hydrate is a non-denaturing detergent used for the extraction of membrane proteins.

Application

Sodium cholate hydrate has been used in a study to assess infiltration of pressurized promoter solutions in a mesoporous silica. [1]
Sodium cholate hydrate has been used:
  • as a component of biofilm growth media along with tryptic soy broth (TSB) to test the effects of each bile salt on biofilm formation
  • as a detergent to study its effect on cannabinoid receptor 1 (CB1) detection by western blot
  • as a promoter to prepare solution B for the synthesis of tungsten disulfide (WS2) on a SiO2/Si wafer

Features and Benefits

  • pH range 5-8
  • Suitable for membrane technology and culture media

Hazard Statements

H412

Precautionary Statements

P273 - P501

Hazard Classifications

Aquatic Chronic 3

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000361927
    0000361927
    0000378209
    0000378217
    0000364263

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    Fang Fang et al.
    Journal of bacteriology, 191(18), 5743-5757 (2009-07-14)
    Commensal lactobacilli frequently produce bile salt hydrolase (Bsh) enzymes whose roles in intestinal survival are unclear. Twenty-six Lactobacillus salivarius strains from different sources all harbored a bsh1 allele on their respective megaplasmids. This allele was related to the plasmid-borne bsh1
    Infiltration of pressurized promoter solutions in a mesoporous silica
    Punyamurtula and Qiao
    Microporous Mater., 103, 5-5 (2007)
    Mavis Jiarong Li et al.
    Current protocols in protein science, 98(1), e100-e100 (2019-11-21)
    Lipid nanodiscs provide a native-like lipid environment for membrane proteins, and they have become a valuable platform for the study of membrane biophysics. A range of biophysical and biochemical analyses are enabled when membrane proteins are captured in lipid nanodiscs.
    F Peter Guengerich et al.
    Nature protocols, 4(9), 1245-1251 (2009-08-08)
    Cytochrome P450 (P450) enzymes are important in the metabolism of steroids, vitamins, carcinogens, drugs and other compounds. Two of the commonly used assays in this field are the measurements of total P450 and NADPH-P450 reductase in biological preparations. A detailed
    Volkan K Köseoğlu et al.
    Infection and immunity, 87(7) (2019-04-17)
    Shigella flexneri is an intracellular bacterial pathogen that invades epithelial cells in the colonic mucosa, leading to bloody diarrhea. A previous study showed that S. flexneri forms biofilms in the presence of bile salts, through an unknown mechanism. Here, we
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