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39235

Sigma-Aldrich

11-[5-(Dimethylamino)-1-naphthalenesulfonylamino]undecanoic acid

BioReagent, suitable for fluorescence, ≥98.0% (TLC)

Synonym(s):

11-(Dansylamino)undecanoic acid, DAUDA

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About This Item

Empirical Formula (Hill Notation):
C23H34N2O4S
CAS Number:
73025-02-2
Molecular Weight:
434.59
Beilstein:
8946533
MDL number:
MFCD00467271
UNSPSC Code:
12352200
PubChem Substance ID:
57649887

product line

BioReagent

Assay

≥98.0% (TLC)

solubility

DMSO: soluble
methanol: soluble

fluorescence

λex 335 nm; λem 516 nm in methanol

suitability

suitable for fluorescence

storage temp.

2-8°C

SMILES string

CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCCCCCCCCC(O)=O

InChI

1S/C23H34N2O4S/c1-25(2)21-15-11-14-20-19(21)13-12-16-22(20)30(28,29)24-18-10-8-6-4-3-5-7-9-17-23(26)27/h11-16,24H,3-10,17-18H2,1-2H3,(H,26,27)

InChI key

CEPGVMDMVJGHFQ-UHFFFAOYSA-N

Application

11-[5-(Dimethylamino)-1-naphthalenesulfonylamino]undecanoic acid (DAUDA), a dansyl-type fluorophore, is widely used as a hydrophobic binding site probe to identify and characterize the binding sites of medium chain fatty acids, their derivatives and other hydrophobic compounds on molecules such as proteins.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

HPLC determination of fatty acid binding proteins in rat liver with fluorescence detection

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCC4452
BCBZ5697
BCBV8084
BCBS7918V
BCBR2159V

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O K Gasymov et al.
Biochimica et biophysica acta, 1433(1-2), 307-320 (1999-10-09)
The principal lipid binding protein in tears, tear lipocalin (TL), binds acid and the fluorescent fatty acid analogs, DAUDA and 16-AP at one site TL compete for this binding site. A fluorescent competitive binding assay revealed that apo-TL has a
A E Thumser et al.
The Biochemical journal, 320 ( Pt 3), 729-733 (1996-12-15)
The physiological role of liver fatty acid-binding protein (L-FABP) has yet to be clarified. An important feature of this member of the family of intracellular lipid-binding proteins is the wide range of compounds that have been identified as potential physiological
Fen Qiao et al.
PloS one, 11(8), e0160003-e0160003 (2016-08-02)
Heterodera avenae and H. filipjevi are major parasites of wheat, reducing production worldwide. Both are sedentary endoparasitic nematodes, and their development and parasitism depend strongly on nutrients obtained from hosts. Secreted fatty acid- and retinol-binding (FAR) proteins are nematode-specific lipid
A Timanova et al.
European journal of biochemistry, 261(2), 569-576 (1999-04-24)
A fatty acid-binding protein from the nematode Ascaridia galli was characterized. The gene was isolated and recombinantly expressed in Escherichia coli. According to the deduced amino acid sequence A. galli fatty acid-binding protein (AgFABP) belongs to the family of nematode
M W Kennedy et al.
The Journal of biological chemistry, 272(47), 29442-29448 (1997-12-31)
Ov20 is a major antigen of the parasitic nematode Onchocerca volvulus, the causative agent of river blindness in humans, and the protein is secreted into the tissue occupied by the parasite. DNA encoding Ov20 was isolated, and the protein was
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