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37920

Sigma-Aldrich

6,8-Dihydroxy-1,3-pyrenedisulfonic acid disodium salt

BioReagent, suitable for fluorescence, ≥97.0% (HPCE)

Synonym(s):

DHPDS, Disodium 6,8-dihydroxy-1,3-pyrenedisulfonate

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100 MG
CN¥3,469.86

CN¥3,469.86

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100 MG
CN¥3,469.86

About This Item

Empirical Formula (Hill Notation):
C16H8Na2O8S2
CAS Number:
61255-63-8
Molecular Weight:
438.34
Beilstein:
8962638
MDL number:
MFCD00800283
UNSPSC Code:
12352106
PubChem Substance ID:
57649723
NACRES:
NA.32

CN¥3,469.86

Please contact Customer Service for Availability
Request a Bulk Order

product line

BioReagent

Assay

≥97.0% (HPCE)

form

powder

pKa 

7.33
8.53

mp

≥250 °C (lit.)

solubility

DMF: soluble
H2O: soluble
methanol: soluble

fluorescence

λex 405 nm; λem 456 nm in 0.1 M citrate pH 3.0
λex 458 nm; λem 498 nm in 0.1 M Tris pH 8.0

suitability

suitable for fluorescence

SMILES string

[Na+].[Na+].Oc1cc(O)c2ccc3c(cc(c4ccc1c2c34)S([O-])(=O)=O)S([O-])(=O)=O

InChI

1S/C16H10O8S2.2Na/c17-11-5-12(18)8-2-4-10-14(26(22,23)24)6-13(25(19,20)21)9-3-1-7(11)15(8)16(9)10;;/h1-6,17-18H,(H,19,20,21)(H,22,23,24);;/q;2*+1/p-2

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6,8-Dihydroxy-1,3-pyrenedisulfonic acid disodium salt BioReagent, suitable for fluorescence, ≥97.0% (HPCE)

37920

6,8-Dihydroxy-1,3-pyrenedisulfonic acid disodium salt

Chromotropic acid disodium salt dihydrate puriss. p.a., ACS reagent, for the detection of Ag, ClO3-, Cr, Hg, NO2-, NO32-, Ti, ≥98.0%

27150

Chromotropic acid disodium salt dihydrate

1-Pyrenesulfonic acid sodium salt suitable for fluorescence, ≥97.0% (HPLC)

82657

1-Pyrenesulfonic acid sodium salt

8-Octanoyloxypyrene-1,3,6-trisulfonic acid trisodium salt suitable for fluorescence, ≥90% (HPCE)

74875

8-Octanoyloxypyrene-1,3,6-trisulfonic acid trisodium salt

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

solubility

DMF: soluble, methanol: soluble, H2O: soluble

solubility

-

solubility

-

solubility

DMF: soluble, DMSO: soluble, H2O: soluble, methanol: soluble

mp

≥250 °C (lit.)

mp

>300 °C (lit.)

mp

233-236 °C (lit.)

mp

251-260 °C (lit.)

form

powder

form

powder

form

powder

form

powder

product line

BioReagent

product line

-

product line

-

product line

-

Application

6,8-Dihydroxy-1,3-pyrenedisulfonic acid (DHPDS) is a pH-sensitive dye that may be used to measure pH changes inside cells (pHi). DHPDS is used to create charge transfer complexes for studies on nanostructure assembly.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Highly water soluble pH indicator for the physiological range[1]

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
  • Specification Sheet

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    BCCL2397
    BCCK4049
    BCCD3359
    BCCB8675
    1377203V

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    Find documentation for the products that you have recently purchased in the Document Library.

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    Chao Wang et al.
    Langmuir : the ACS journal of surfaces and colloids, 26(18), 14509-14511 (2010-08-21)
    We have demonstrated a hierarchical self-assembly of the nanoribbons on the basis of the concept of a superamphiphile. A viologen-containing surfactant (RV) and a water-soluble electron donor, 6,8-dihydroxypyrene-1,3-disulfonic acid disodium (DHP), are mixed in water to form a charge transfer
    K Hanaoka et al.
    Nihon rinsho. Japanese journal of clinical medicine, 50(9), 2048-2053 (1992-09-01)
    Since various cellular processes depend on changes in pH, the regulation of intracellular pH (pHi) is important both for the individual cell and for the organism. The mechanisms of the regulation of pHi can be investigated by monitoring pHi. In
    Aron Hakonen et al.
    Talanta, 80(5), 1964-1969 (2010-02-16)
    This study presents a high-performance ratiometric pH optode based on the fluorophore 6,8-dihydroxypyrene-1,3-disulfonic acid (DHPDS). The two pH-sensitive terminal hydroxy groups of DHPDS facilitated dual excitation/dual emission (F(1): lambda(1,ex)=420 nm, lambda(1,em)=462 nm; F(2): lambda(2,ex)=470 nm, lambda(2,em)=498 nm) properties for ratiometric
    F X Felberbauer et al.
    Pflugers Archiv : European journal of physiology, 419(2), 215-217 (1991-09-01)
    The pH-sensitive fluorescent dye 1,3-dihydroxy-pyrene-6,8-disulfonic acid (DHPDS) was used to measure intracellular pH (pHi) from the surface fluorescence of the isolated perfused rat liver. Monochromatic light from a fluorometer was focused on the liver with a fiber optic, emitted light
    O.S. Wolfbeis et al.
    Fresenius Journal of Analytical Chemistry, 314, 119-119 (1983)

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