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Key Documents

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34869

Sigma-Aldrich

Dimethyl sulfoxide

suitable for HPLC, ≥99.7%

Synonym(s):

DMSO

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100 EA
CN¥749.85

CN¥749.85

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100 EA
CN¥749.85

About This Item

Linear Formula:
(CH3)2SO
CAS Number:
67-68-5
Molecular Weight:
78.13
Beilstein:
506008
EC Number:
200-664-3
MDL number:
MFCD00002089
UNSPSC Code:
41116105
PubChem Substance ID:
329755076
NACRES:
NA.21
grade:
HPLC grade
technique(s):
HPLC: suitable
application(s):
food and beverages
bp:
189 °C (lit.)
vapor pressure:
0.42 mmHg ( 20 °C)

CN¥749.85

Please contact Customer Service for Availability
Request a Bulk Order

grade

HPLC grade

Quality Level

100

vapor density

2.7 (vs air)

vapor pressure

0.42 mmHg ( 20 °C)

Assay

≥99.7%

form

liquid

autoignition temp.

573 °F

expl. lim.

42 %, 63 °F

technique(s)

HPLC: suitable

impurities

≤0.002% non-volatile matter
≤0.2% water (Karl Fischer)

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This Item
SU860093SU86009027426
Closures for Snap Ring vials polypropylene seal, PTFE/silicone (with starburst), thread for 11 mm (snap ring), pkg of 100 ea

27427

Closures for Snap Ring vials

Closures for Snap Ring vials clear polyethylene cap, red PTFE/silicone, thread for 11 mm (snap ring), pkg of 100 ea

SU860093

Closures for Snap Ring vials

Closures for Snap Ring vials clear polyethylene cap, PTFE/red rubber, thread for 11 mm snap ring, pkg of 100 ea

SU860090

Closures for Snap Ring vials

Closures for Snap Ring vials polypropylene seal, PTFE/silicone (with slit), thread for 11 mm snap ring, pkg of 100 ea

27426

Closures for Snap Ring vials

fitting

thread for 11 mm (snap ring)

fitting

thread for 11 mm (snap ring)

fitting

thread for 11 mm snap ring

fitting

thread for 11 mm snap ring

compatibility

for use with Large Opening Crimp/Snap Seal Vials

compatibility

for use with Large Opening Crimp/Snap Seal Vials

compatibility

for use with Large Opening Crimp/Snap Seal Vials

compatibility

for use with Large Opening Crimp/Snap Seal Vials

feature

closure type snap ring seal

feature

closure type clear polyethylene snap cap

feature

closure type clear polyethylene snap cap

feature

closure type snap ring seal

packaging

pkg of 100 ea

packaging

pkg of 100 ea

packaging

pkg of 100 ea

packaging

pkg of 100 ea

O.D. × H × I.D.

11.5 mm × 6 mm × 9 mm

O.D. × H × I.D.

11.5 mm × 6 mm × 9 mm

O.D. × H × I.D.

11.5 mm × 6 mm × 9 mm

O.D. × H × I.D.

11.5 mm × 6 mm × 9 mm

General description

Dimethyl sulfoxide (DMSO) is a polar organic solvent.[1] DMSO activated by various electrophiles (oxalyl chloride) has been used to oxidize various alcohols (primary, secondary, allylic, benzylic, hindered and bicyclic). Carbonyl compounds are formed as reaction products.[2] Due to its higher stability, it has been proposed as an alternate solvent for methyl cellosolve for use in ninhydrin reaction.[3]

Application

Suitable for HPLC, spectrophotometry, environmental testing

Caution

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

Other Notes

For information on dimethyl sulfoxide miscibility, please visit the following link:
Dimethyl Sulfoxide Miscibility/Immiscibility Table
Important notice
  • The article number 34869-4X2.5L will be discontinued. Please order the single bottle 34869-2.5L which is physically identical with the same exact specifications.
  • The article number 34869-6X1L will be discontinued. Please order the single bottle 34869-1L which is physically identical with the same exact specifications.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

188.6 °F - closed cup

Flash Point(C)

87 °C - closed cup

  • Specification Sheet

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    SHBS5662
    SHBS4083
    STBL4703
    STBL4704
    STBL4498

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    If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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    Find documentation for the products that you have recently purchased in the Document Library.

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    1. What is the molarity of DMSO?

      DMSO will have a molarity of 14.1M, based on a density of 1.1 g/mL and a molecular weight of 78.13 g/mol.

    2. What is the DMSO dissolved in?

      DMSO is not dissolved in any solvent. It is a pure chemical compound that is a liquid at room temperature.

    3. Where does DMSO come from?

      DMSO is known to have been isolated from tree bark in the past. It is now a commericially synthesized solvent.

    4. Which document(s) contains shelf-life or expiration date information for a given product?

      If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

    5. Dimethyl sulfoxide (DMSO) should be a liquid.  Why did it arrive as a solid?

      DMSO supercools easily, and re-melts slowly at room temperature. The melting point is 16-19 °C. The solidified product can be re-liquefied by warming to room temperature without detriment to the product.

    6. How do I get lot-specific information or a Certificate of Analysis?

      The lot specific COA document can be found by entering the lot number above under the "Documents" section.

    7. How do I find price and availability?

      There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

    8. Is Dimethyl sulfoxide a sterile product?

      No, this product is not considered sterile.  Product Nos. D2560 and D2438 are sterile-filtered.

    9. What is the Department of Transportation shipping information for this product?

      Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

    10. My question is not addressed here, how can I contact Technical Service for assistance?

      Ask a Scientist here.

    Oxidation of alcohols by ?activated? dimethyl sulfoxide. A preparative, steric and mechanistic study.
    Omura K and Swern D.
    Tetrahedron, 34(11), 1651-1660 (1978)
    Amino acid analysis: aqueous dimethyl sulfoxide as solvent for the ninhydrin reaction.
    S Moore
    The Journal of biological chemistry, 243(23), 6281-6283 (1968-12-10)
    A RAPID PERMETHYLATION OF GLYCOLIPID, AND POLYSACCHARIDE CATALYZED BY METHYLSULFINYL CARBANION IN DIMETHYL SULFOXIDE.
    S HAKOMORI
    Journal of biochemistry, 55, 205-208 (1964-02-01)
    Claudia C Faria et al.
    Cancer research, 75(1), 134-146 (2014-11-14)
    Medulloblastoma is the most common malignant pediatric brain tumor, with metastases present at diagnosis conferring a poor prognosis. Mechanisms of dissemination are poorly understood and metastatic lesions are genetically divergent from the matched primary tumor. Effective and less toxic therapies
    Mike Clements et al.
    Toxicological sciences : an official journal of the Society of Toxicology, 140(2), 445-461 (2014-05-09)
    Human stem cell derived cardiomyocytes (hESC-CM) provide a potential model for development of improved assays for pre-clinical predictive drug safety screening. We have used multi-electrode array (MEA) analysis of hESC-CM to generate multi-parameter data to profile drug impact on cardiomyocyte
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