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D4540

Dimethyl sulfoxide

Name: Dimethyl sulfoxide
Brand: SIGMA

≥99.5% (GC), suitable for plant cell culture

Synonym(s):

DMSO

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About This Item

Linear Formula:

(CH₃)₂SO

CAS Number:

67-68-5

Molecular Weight:

78.13

UNSPSC Code:

12191502

NACRES:

NA.71

PubChem Substance ID:

24893881

EC Number:

200-664-3

Beilstein/REAXYS Number:

506008

MDL number:

MFCD00002089

Assay:

≥99.5% (GC)

Technique(s):

cell culture | plant: suitable, cryopreservation: suitable

Bp:

189 °C (lit.)

Vapor pressure:

0.42 mmHg ( 20 °C)

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Properties

vapor density

2.7 (vs air)

Quality Level

200

vapor pressure

0.42 mmHg ( 20 °C)

assay

≥99.5% (GC)

form

liquid

autoignition temp.

573 °F

expl. lim.

42 %, 63 °F

technique(s)

cell culture | plant: suitable, cryopreservation: suitable

impurities

<0.1% water (Karl Fischer)

color

colorless

refractive index

n20/D 1.479 (lit.)

bp

189 °C (lit.)

mp

16-19 °C (lit.)

solubility

H₂O: miscible (completely)

density

1.10 g/mL (lit.)

SMILES string

CS(C)=O

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

Description

Application

Dimethyl sulfoxide has been used:

in the preparation of bisphenol A (BPA)
in cell proliferation assay (MTT assay)
in chemosensitivity assay
as the vehicle control in all experiments like apoptosis assay
in ethoxyresorufin-O-deethylation (EROD) assay

Biochem/physiol Actions

DMSO (dimethyl sulfoxide), an organic solvent possesses several pharmaceutical activities such as analgesic, diuretic, bacteriostatic, membrane-penetrant, anti-inflammatory, vasodilatory and cholinesterase inhibitory effects. It is a by-product of the lumber industry and used as an industrial solvent. DMSO also serves as a therapeutic agent to treat interstitial cystitis and arthritis.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Disclaimer

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Articles

Good Cell Banking Practices

Overview of good cell banking practices for cell line cryopreservation purposes.

良好的细胞库操作实践

用于细胞系冷冻保存的良好细胞库操作实践概述。

Cell Culture Fundamentals: Cryopreservation and Storage of Cell Lines

Overview on liquid nitrogen storage and freezing of cell stocks for cell line cryopreservation purposes. Free ECACC handbook download.

Curcumin promotes apoptosis, increases chemosensitivity, and inhibits nuclear factor kappaB in esophageal adenocarcinoma

Hartojo W, et al.

Translational Oncology, 3(2), 99-108 (2010)

Pharmacotherapy of joint and tendon disease

Equine Sports Medicine and Surgery E-Book: Basic and clinical sciences of the equine athlete, 473-473 (2013)

Evaluation of the sub-lethal toxicity of Cu, Pb, bisphenol A and polychlorinated biphenyl to the marine dinoflagellate Cochlodinium polykrikoides

Ebenezer V and Ki J S

Algae, 27(1), 63-63 (2012)

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Global Trade Item Number

SKU	GTIN
D4540-1L	04061838259295
D4540-100ML	04061838259288
D4540-500ML	04061838259301