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1.01900

Supelco

Dimethyl sulfoxide

for headspace gas chromatography SupraSolv®

Synonym(s):

Methanesulfinylmethane, Methyl sulfoxide, Dimethyl(oxido)sulfur, DMSO, DMSO

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About This Item

Linear Formula:
(CH3)2SO
CAS Number:
Molecular Weight:
78.13
Beilstein:
506008
MDL number:
UNSPSC Code:
12191502
EC Index Number:
200-664-3
NACRES:
NA.03

Agency

according to Ph. Eur.
according to USP

Quality Level

vapor density

2.7 (vs air)

vapor pressure

0.42 mmHg ( 20 °C)

product line

SupraSolv®

Assay

≥99.8% (GC)

form

liquid

autoignition temp.

573 °F

potency

28300 mg/kg LD50, oral (Rat)
40000 mg/kg LD50, skin (Rat)

expl. lim.

42 %, 63 °F

technique(s)

GC-HS: suitable

impurities

≤0.05% Water

evapn. residue

≤3.0 mg/L

color

APHA: ≤10

refractive index

n20/D 1.479 (lit.)

kinematic viscosity

2.14 cSt

bp

189 °C (lit.)

mp

16-19 °C (lit.)

transition temp

flash point 87 °C

density

1.10 g/mL (lit.)

storage temp.

2-30°C

SMILES string

CS(C)=O

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

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General description

SupraSolv solvents for headspace gas chromatography are developed particularly for the analysis of residual
solvents in drug substances, excipients and drug products according to ICH, Ph Eur and USP - SupraSolv headspace solvents are tested for all
residual solvents defined by the ICH.

Caution

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

Specifications

Saturation Concentration in Air: 8.0 g/m3 (20 °C)

Analysis Note

Purity (GC): ≥ 99.8 %
Identity (IR): conforms
Evaporation residue: ≤ 3.0 mg/l
Water: ≤ 0.05 %
Color: ≤ 10 Hazen
GC/HS (Every residual solvent of class 1acc. ICH): ≤ 1 µg/g
GC/HS (Every residual solvent of class 2acc. ICH): ≤ 10 µg/g
GC/HS (Every residual solvent of class 3acc. ICH): ≤ 50 µg/g
Suitable as solvent for the analysis of residual solvents of ICH classes 1,2 and 3 according to Ph Eur and USP.
Formic acid, acetic acid, dimethylacetamide and cumene are not detected.

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

SUPRASOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

188.6 °F - closed cup

Flash Point(C)

87 °C - closed cup


Certificates of Analysis (COA)

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