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Safety Information

A5000

Sigma-Aldrich

Acetaminophen

meets USP testing specifications, 98.0-102.0%, powder

Synonym(s):

4′-Hydroxyacetanilide, 4-Acetamidophenol, N-(4-Hydroxyphenyl)acetamide, N-Acetyl-4-aminophenol, APAP, Paracetamol

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About This Item

Linear Formula:
CH3CONHC6H4OH
CAS Number:
103-90-2
Molecular Weight:
151.16
Beilstein:
2208089
MDL number:
MFCD00002328
UNSPSC Code:
12352111
PubChem Substance ID:
24890930
NACRES:
NA.25
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Agency

USP/NF
meets USP testing specifications

Quality Level

200

Assay

98.0-102.0%

form

powder

mp

168-172 °C (lit.)

solubility

DMSO: 5 M
ethanol: 50 mg/mL
H2O: very slightly soluble

application(s)

pharmaceutical (small molecule)

SMILES string

CC(=O)Nc1ccc(O)cc1

InChI

1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)

InChI key

RZVAJINKPMORJF-UHFFFAOYSA-N

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Show Differences

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This Item
A3035A7085A064
对乙酰氨基酚 meets USP testing specifications, 98.0-102.0%, powder

A5000

对乙酰氨基酚

对乙酰氨基酚 analytical standard

A3035

对乙酰氨基酚

对乙酰氨基酚 BioXtra, ≥99.0%

A7085

对乙酰氨基酚

醋氨酚 溶液 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

A064

醋氨酚 溶液

assay

98.0-102.0%

assay

-

assay

≥99.0%

assay

-

Quality Level

200

Quality Level

300

Quality Level

200

Quality Level

300

solubility

DMSO: 5 M, H2O: very slightly soluble, ethanol: 50 mg/mL

solubility

-

solubility

ethanol: 0.5 M, clear, colorless

solubility

-

agency

USP/NF

agency

-

agency

-

agency

-

mp

168-172 °C (lit.)

mp

168-172 °C (lit.)

mp

168-172 °C (lit.)

mp

-

Application

Analgesic.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

364.3 °F - Pensky-Martens closed cup

Flash Point(C)

184.6 °C - Pensky-Martens closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品
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    Certificates of Analysis (COA)

    Lot/Batch Number
    MKCX1247
    MKCV4785
    MKCT8276
    MKCT3819
    MKCS3304

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    Mohammad A Rahman et al.
    Scientific reports, 9(1), 6571-6571 (2019-04-27)
    Cellular CYP2E1 is well-known to mediate alcohol- (ALC) and acetaminophen- (APAP) induced toxicity in hepatic and extra-hepatic cells. Although exosomes have been gaining importance in understanding mechanism of intra- and inter-cellular communication, the functional role of drug metabolizing cytochrome P450
    S M de Morais et al.
    Gastroenterology, 102(2), 577-586 (1992-02-01)
    Gilbert's syndrome occurs in 5%-7% of the human population and is caused by an inherited deficiency in the glucuronidation of endogenous bilirubin, resulting in its accumulation and jaundice. The authors of the present study have previously shown that rats with
    Garry G Graham et al.
    Inflammopharmacology, 21(3), 201-232 (2013-05-31)
    Paracetamol is used worldwide for its analgesic and antipyretic actions. It has a spectrum of action similar to that of NSAIDs and resembles particularly the COX-2 selective inhibitors. Paracetamol is, on average, a weaker analgesic than NSAIDs or COX-2 selective
    Edward Munsterhjelm et al.
    Anesthesiology, 103(4), 712-717 (2005-09-30)
    Acetaminophen (paracetamol) is widely used for postoperative analgesia. Its mechanism of action is inhibition of prostaglandin synthesis in the central nervous system, and acetaminophen is traditionally not considered to influence platelet function. The authors studied the dose-dependent inhibition of platelet
    Karel Allegaert et al.
    Archives of disease in childhood, 98(6), 462-466 (2013-04-23)
    There remains a need for alternative medical treatments for patent ductus arteriosus (PDA) closure in extreme preterm neonates because of therapeutic failure and adverse effects associated with non-selective cyclo-oxygenase inhibitors. Reports of an association between paracetamol exposure and PDA closure
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