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关于此项目
线性分子式:
CH3CONHC6H4OH
化学文摘社编号:
分子量:
151.16
UNSPSC Code:
12352111
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2208089
Quality Level
agency
USP/NF, meets USP testing specifications
assay
98.0-102.0%
form
powder
mp
168-172 °C (lit.)
solubility
DMSO: 5 M, ethanol: 50 mg/mL, H2O: very slightly soluble
application(s)
pharmaceutical (small molecule)
SMILES string
CC(=O)Nc1ccc(O)cc1
InChI
1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)
InChI key
RZVAJINKPMORJF-UHFFFAOYSA-N
Gene Information
human ... FAAH(2166), PTGS1(5742), PTGS2(5743), TRPV1(7442)
Application
镇痛剂。
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
flash_point_f
364.3 °F - Pensky-Martens closed cup
flash_point_c
184.6 °C - Pensky-Martens closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
涉药品监管产品
此项目有
Mohammad A Rahman et al.
Scientific reports, 9(1), 6571-6571 (2019-04-27)
Cellular CYP2E1 is well-known to mediate alcohol- (ALC) and acetaminophen- (APAP) induced toxicity in hepatic and extra-hepatic cells. Although exosomes have been gaining importance in understanding mechanism of intra- and inter-cellular communication, the functional role of drug metabolizing cytochrome P450
Garry G Graham et al.
Drug safety, 28(3), 227-240 (2005-03-01)
The excellent tolerability of therapeutic doses of paracetamol (acetaminophen) is a major factor in the very wide use of the drug. The major problem in the use of paracetamol is its hepatotoxicity after an overdose. Hepatotoxicity has also been reported
Garry G Graham et al.
Inflammopharmacology, 21(3), 201-232 (2013-05-31)
Paracetamol is used worldwide for its analgesic and antipyretic actions. It has a spectrum of action similar to that of NSAIDs and resembles particularly the COX-2 selective inhibitors. Paracetamol is, on average, a weaker analgesic than NSAIDs or COX-2 selective
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A5000-1KG | 04061833375303 |
| A5000-100G | 04061835542192 |
| A5000-500G | 04061833375310 |
