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A3035

对乙酰氨基酚

analytical standard

别名:

4′-羟基乙酰苯胺, 4-乙酰氨基酚, N-(4-羟基苯基)乙酰胺, N-乙酰基-4-氨基苯酚, APAP, 扑热息痛

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关于此项目

线性分子式:
CH3CONHC6H4OH
化学文摘社编号:
103-90-2
分子量:
151.16
UNSPSC Code:
41116107
NACRES:
NA.21
PubChem Substance ID:
24890717
EC Number:
203-157-5
Beilstein/REAXYS Number:
2208089
MDL number:
MFCD00002328
Form:
powder
Quality level:
300
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grade

analytical standard

Quality Level

300

form

powder

packaging

vial of 1 g

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

168-172 °C (lit.)

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

SMILES string

CC(=O)Nc1ccc(O)cc1

InChI

1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)

InChI key

RZVAJINKPMORJF-UHFFFAOYSA-N

Gene Information

human ... FAAH(2166), PTGS1(5742), PTGS2(5743), TRPV1(7442)

Application

镇痛剂。

Packaging

棕色螺纹盖样品瓶包装

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

364.3 °F - Pensky-Martens closed cup

flash_point_c

184.6 °C - Pensky-Martens closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

涉药品监管产品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000366465
0000366465
0000373099
0000373100
0000366464

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Garry G Graham et al.
Drug safety, 28(3), 227-240 (2005-03-01)
The excellent tolerability of therapeutic doses of paracetamol (acetaminophen) is a major factor in the very wide use of the drug. The major problem in the use of paracetamol is its hepatotoxicity after an overdose. Hepatotoxicity has also been reported
Garry G Graham et al.
Inflammopharmacology, 21(3), 201-232 (2013-05-31)
Paracetamol is used worldwide for its analgesic and antipyretic actions. It has a spectrum of action similar to that of NSAIDs and resembles particularly the COX-2 selective inhibitors. Paracetamol is, on average, a weaker analgesic than NSAIDs or COX-2 selective
Mitchell R McGill et al.
Pharmaceutical research, 30(9), 2174-2187 (2013-03-07)
Acetaminophen (APAP) is one of the most widely used drugs. Though safe at therapeutic doses, overdose causes mitochondrial dysfunction and centrilobular necrosis in the liver. The first studies of APAP metabolism and activation were published more than 40 years ago.
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全球贸易项目编号

货号GTIN
A3035-5VL04061833360217
A3035-1VL04061833360200