All Photos(3)

Documents

933856

γ-Valerolactone

Name: γ-Valerolactone
Brand: SIAL

BioRenewable, anhydrous, DMF and NMP substitute, ≥99%

Synonym(s):

4,5-Dihydro-5-methyl-2(3H)-furanone, GVL, γ-Methyl-γ-butyrolactone, 4,5-Dihydro-5-methyl-2(3H)-furanone, 4-Hydroxypentanoic acid lactone

Sign Into View Organizational & Contract Pricing

All Photos(3)

About This Item

Empirical Formula (Hill Notation):

C₅H₈O₂

CAS Number:

108-29-2

Molecular Weight:

100.12

Beilstein:

80420

MDL number:

MFCD00005400

UNSPSC Code:

12352100

NACRES:

NA.21

vapor density

3.45 (vs air)

Quality Level

200

Assay

≥99%

form

liquid

greener alternative product characteristics

Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

impurities

≤50 ppm water

color

colorless to light yellow

refractive index

n20/D 1.432 (lit.)

bp

207-208 °C (lit.)
82-85 °C/10 mmHg (lit.)

mp

−31 °C (lit.)

density

1.05 g/mL at 25 °C (lit.)

greener alternative category

, Aligned

SMILES string

CC1CCC(=O)O1

InChI

1S/C5H8O2/c1-4-2-3-5(6)7-4/h4H,2-3H2,1H3

InChI key

GAEKPEKOJKCEMS-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Greener Alternative Products

General description

We are committed to providing environmentally friendly products, and γ-Valerolactone (GVL) is a prime example of our dedication to this effort. GVL is a bio-based solvent derived from renewable sources, which makes it a sustainable alternative to traditional organic solvents like NMP and DMF. GVL aligns with the principles of "Use of Renewable Feedstocks" and "Safer Solvents and Auxiliaries" and offers exceptional solubility properties. As a result, it is an effective solvent for various applications, such as chemical synthesis. GVL is non-toxic, non-irritating, and biodegradable, making it a safe and eco-friendly choice for both consumers and the environment. Overall, γ-Valerolactone is an excellent option for companies and researchers seeking to reduce their environmental footprint while still delivering high-quality products.

Application

Peptide synthesis
Cross-coupling reactions
Nonaqueous redox-flow batteries
Polymerization reaction
Extraction

Features and Benefits

Bio-based
Made from Renewable Resource - rice
Biodegradable
Non-toxic
Low vapor pressure

related product

Product No.

Description

Pricing

Signal Word

Warning

Hazard Statements

H315,H319

Precautionary Statements

P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

204.8 °F - closed cup

Flash Point(C)

96 °C - closed cup

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

SHBR4720

SHBQ9522

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Greening Fmoc/tBu solid-phase peptide synthesis

Musaimi O A, et al.

Green Chemistry, 22, 996-1018 (2020)

γ-Valerolactone (GVL): An eco-friendly anchoring solvent for solid-phase peptide synthesis

Musaimi O A, et al.

Tetrahedron Letters, 60, 151058-151058 (2019)

γ-Valerolactone as a Green Solvent for Extracting Carboxylic Acids and Alcohols from n-Tetradecane: Equilibrium Data for Model Systems at 298.15 K

Carlos E. S. Dantas and Roberta Ceriani

Journal of Chemical and Engineering Data, Volume 67, Issue 6, 1460?1473-1460?1473 (2022)

γ-valerolactone (GVL) as a bio-based green solvent and ligand for iron-mediated AGET ATRP

XianRong Shen, DengZhou Xia, YiXin Xiang and JianGang Gao

e-Polymers, 19, 323-329 (2019)

Microwave-Assisted Green Solid-Phase Peptide Synthesis Using γ-Valerolactone (GVL) as Solvent

Kumar A, et al.

ACS sustainable chemistry & engineering, 6, 8034?8039-8034?8039 (2018)

View All Related Papers