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901765

Sigma-Aldrich

Dde biotin-azide

Synonym(s):

rel-(3aR,4R,6aS)-N-[19-Azido-15-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3,6,9,12-tetraoxa-16-azanonadec-1-yl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide

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About This Item

Empirical Formula (Hill Notation):
C32H53N7O8S
CAS Number:
Molecular Weight:
695.87
MDL number:
UNSPSC Code:
12352125
NACRES:
NA.22

form

liquid

reaction suitability

reaction type: click chemistry

storage temp.

−20°C (−15°C to −25°C)

Application

Extraordinary strength of the streptavidin-biotin interaction allows for efficient capturing of even highly dilute targets; however, it makes recovery of proteins from affinity resins challenging. This reagent contains a biotin moiety linked to an azide moiety through a spacer arm containing a hydrazine-cleavable Dde linker. Typically >90% of captured biomolecules can be efficiently released.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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