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Key Documents

Safety Information

913669

Sigma-Aldrich

Biotinamidoethyldisulfanyl(2-aminoethane) trifluoroacetic acid

Synonym(s):

N-(2-((2-Aminoethyl)disulfaneyl)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide 2,2,2-trifluoroacetate, Biotin-SS-NH2 TFA, Biotin-cystamine TFA, Cleavable biotin linker

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25 MG
¥913.03
100 MG
¥3,043.46
500 MG
¥9,949.75

¥913.03


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25 MG
¥913.03
100 MG
¥3,043.46
500 MG
¥9,949.75

About This Item

Empirical Formula (Hill Notation):
C16H27F3N4O4S3
CAS Number:
Molecular Weight:
492.60
MDL number:
UNSPSC Code:
12352106
NACRES:
NA.22

¥913.03


Please contact Customer Service for Availability

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form

powder

Quality Level

storage temp.

−20°C

SMILES string

OC(C(F)(F)F)=O.NCCSSCCNC(CCCC[C@H]1[C@]2([H])[C@](NC(N2)=O)([H])CS1)=O

InChI

1S/C14H26N4O2S3.C2HF3O2/c15-5-7-22-23-8-6-16-12(19)4-2-1-3-11-13-10(9-21-11)17-14(20)18-13;3-2(4,5)1(6)7/h10-11,13H,1-9,15H2,(H,16,19)(H2,17,18,20);(H,6,7)/t10-,11-,13-;/m0./s1

InChI key

IEBCHCOZFAGWJW-SQRKDXEHSA-N

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This Item
SAE0063P5521A2237
assay

≥95% (HPLC)

assay

-

assay

-

assay

-

specific activity

≥7000 units/mg protein (At 37 °C with pNPP and DEA as the substrates)

specific activity

-

specific activity

≥2,000 DEA units/mg protein

specific activity

-

concentration

20 mg/mL (ready-to-use)

concentration

-

concentration

≥1.0 mg/mL

concentration

≥900 DEA units/mL

form

buffered aqueous solution (ready-to-use, 20 mg/ml)

form

solution (high-activity)

form

aqueous solution

form

buffered aqueous glycerol solution

shipped in

wet ice

shipped in

wet ice

shipped in

-

shipped in

dry ice

optimum pH

8.0(Stability), 9.8(Activity)

optimum pH

-

optimum pH

-

optimum pH

-

Application

Biotinamidoethyldisulfanyl(2-aminoethane) trifluoroacetic acid (Biotin-SS-NH2 TFA) is a cleavable, biotinylated crosslinkers. The linker can also be used for synthesis of chemical biology tools for labeling target proteins in biological experiments and assays. It possesses dual functionality: enrichment via the biotin and an embedded disulfide bridge for cleavage under reducing conditions.

Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002)

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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