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913669

Sigma-Aldrich

Biotinamidoethyldisulfanyl(2-aminoethane) trifluoroacetic acid

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Synonym(s):
N-(2-((2-Aminoethyl)disulfaneyl)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide 2,2,2-trifluoroacetate, Biotin-SS-NH2 TFA, Biotin-cystamine TFA, Cleavable biotin linker
Empirical Formula (Hill Notation):
C16H27F3N4O4S3
CAS Number:
Molecular Weight:
492.60
UNSPSC Code:
12352106
NACRES:
NA.22

form

powder

Quality Level

storage temp.

−20°C

SMILES string

OC(C(F)(F)F)=O.NCCSSCCNC(CCCC[C@H]1[C@]2([H])[C@](NC(N2)=O)([H])CS1)=O

Application

Biotinamidoethyldisulfanyl(2-aminoethane) trifluoroacetic acid (Biotin-SS-NH2 TFA) is a cleavable, biotinylated crosslinkers. The linker can also be used for synthesis of chemical biology tools for labeling target proteins in biological experiments and assays. It possesses dual functionality: enrichment via the biotin and an embedded disulfide bridge for cleavage under reducing conditions.

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WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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