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79257

Supelco

Tiliroside

analytical standard

Synonym(s):

Astragalin 6"-trans-p-coumarate, Kaempferol 3-O-β-D-(6″-O-(E)-p-coumaroyl)glucopyranoside, Potengriffioside A

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About This Item

Empirical Formula (Hill Notation):
C30H26O13
CAS Number:
20316-62-5
Molecular Weight:
594.52
MDL number:
MFCD00017454
UNSPSC Code:
85151701
PubChem Substance ID:
329768345
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥98% (HPLC)

optical activity

[α]/D -65±8°, c = 0.1 in methanol

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

O[C@H]1[C@H](O)[C@@H](COC(=O)\C=C\c2ccc(O)cc2)O[C@@H](OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)cc5)[C@@H]1O

InChI

1S/C30H26O13/c31-16-6-1-14(2-7-16)3-10-22(35)40-13-21-24(36)26(38)27(39)30(42-21)43-29-25(37)23-19(34)11-18(33)12-20(23)41-28(29)15-4-8-17(32)9-5-15/h1-12,21,24,26-27,30-34,36,38-39H,13H2/b10-3+/t21-,24-,26+,27-,30+/m1/s1

InChI key

DVGGLGXQSFURLP-VWMSDXGPSA-N

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General description

Tiliroside is a glycosidic flavonoid isolated from Helichrysum italicum. It exhibits a variety of pharmacological properties such as anti-inflammatory, antioxidant, anticarcinogenic and hepatoprotective activity.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Tiliroside may be used as a reference standard in the separation and quantification of tiliroside from plant extracts using solid phase extraction (SPE) followed by reversed-phase high-performance liquid chromatography (RP-HPLC).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
BCCD3915
BCBW8460
BCBV4189
BCBR7516V
BCBR5661V

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Michael Timmers et al.
Natural product communications, 7(5), 551-560 (2012-07-18)
On-line (HPLC-NMR) and off-line (HPLC, NMR and MS) methodologies were used to profile the constituents present in the crude extract of Lasiopetalum macrophyllum. On-flow and stop-flow HPLC-NMR supported the presence of trans-tiliroside and permitted partial identification of cis-tiliroside and 4'-methoxy-trans-tiliroside.
Chrisiida Tsimplouli et al.
European journal of nutrition, 51(2), 181-190 (2011-05-21)
Flavonoids have physiological activity and a variety of pharmacological properties, including anticancer activity in vitro, but structure-anticancer activity relationships are unclear. The objectives of this work were to investigate the activity of dietary flavonol congeners against cell lines derived from
Tiliroside and gnaphaliin inhibit human low density lipoprotein oxidation.
Schinella RG, et al.
Fitoterapia, 78(1), 1-6 (2007)
Zijun Luo et al.
Colloids and surfaces. B, Biointerfaces, 92, 84-90 (2011-12-27)
The flavonoids tiliroside, rutin and naringin have been investigated as stabilizers of Pickering oil-in-water (O/W) emulsions. The mean droplet size of tetradecane emulsions was considerably smaller at higher pH, especially for rutin. The solubility of flavonoids in the aqueous phase
Separation and quantification of tiliroside from plant extracts by SPE/RP-HPLC.
Nowak R.
Pharmaceutical biology, 41(8), 627-630 (2003)
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