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Merck
CN

43073

Supelco

Paracetamol β-D-glucuronide

analytical standard

Synonym(s):

p-Acetamidophenyl β-D-glucuronide, Acetaminophen glucuronide

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25 G
¥1,660.00
100 G
¥4,180.06

¥1,660.00


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25 G
¥1,660.00
100 G
¥4,180.06

About This Item

Empirical Formula (Hill Notation):
C14H17NO8
CAS Number:
Molecular Weight:
327.29
Beilstein:
46644
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

¥1,660.00


Please contact Customer Service for Availability

Request a Bulk Order

grade

analytical standard

Quality Level

Assay

≥98.5% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤12.0% water

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

O[C@@H]1[C@@H](O)[C@H](OC2=CC=C(NC(C)=O)C=C2)O[C@H](C(O)=O)[C@H]1O

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PHR1383

Adenine

Adenine ≥99%

A8626

Adenine

Adenine BioReagent, suitable for cell culture

A2786

Adenine

technique(s)

cell culture | plant: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

UV/Vis spectroscopy: suitable

technique(s)

cell culture | mammalian: suitable

assay

≥99%

assay

-

assay

≥99%

assay

≥99%

form

powder

form

-

form

powder

form

powder

application(s)

agriculture

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

-

solubility

0.5 M HCl: soluble 20 mg/mL, clear to slightly hazy, colorless to faintly yellow

solubility

-

solubility

0.5 M HCl: soluble 20 mg/mL, Grade III, colorless to faint yellow or tan

solubility

0.5 M HCl: soluble 20 mg/mL, clear to slightly hazy, colorless to faintly yellow

mp

>360 °C (lit.)

mp

>360 °C (lit.)

mp

>360 °C (lit.)

mp

>360 °C (lit.)

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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María L Ruiz et al.
Drug metabolism and disposition: the biological fate of chemicals, 35(11), 2060-2066 (2007-08-10)
The effect of spironolactone (SL) administration on 17alpha-ethynylestradiol (EE)-induced cholestasis was studied, with emphasis on expression and activity of Mrps. Adult male Wistar rats were divided into the following groups: EE (5 mg/kg daily for 5 days, s.c.), SL (200
Michael Ganetsky et al.
Journal of clinical pharmacology, 53(4), 413-420 (2013-02-26)
Acetaminophen poisoning is the most frequent cause of acute hepatic failure in the US. Toxicity requires reductive metabolism of acetaminophen, primarily via CYP2E1. Liquid acetaminophen preparations contain propylene glycol, a common excipient that has been shown to reduce hepatocellular injury
Marie Lecoeur et al.
Talanta, 205, 120108-120108 (2019-08-28)
In this study, a capillary electrophoresis-tandem mass spectrometry method combining efficient separation and sensitive detection has been developed and validated, for the first time, to quantify acetaminophen and five of its metabolites in urine samples. Optimization of the method has
Lúcia H M L M Santos et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 930, 75-81 (2013-06-04)
Paracetamol is among the most worldwide consumed pharmaceuticals. Although its occurrence in the environment is well documented, data about the presence of its metabolites and transformation products is very scarce. The present work describes the development of an analytical method
Jialin Xu et al.
Drug metabolism and disposition: the biological fate of chemicals, 40(2), 259-266 (2011-10-28)
UDP-glucuronosyltransferases (Ugt) catalyze phase II conjugation reactions with glucuronic acid, which enhances chemical polarity and the elimination from the body. Few studies have addressed whether Ugt expression and activity are affected by liver disease, such as steatosis. The purpose of

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