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Merck
CN

222488

N-(1-Naphthyl)ethylenediamine dihydrochloride

ACS reagent grade, >98%, solid

Synonym(s):

2-(1-Naphthylamino)ethylamine dihydrochloride

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About This Item

Linear Formula:
C10H7NHCH2CH2NH2 · 2HCl
CAS Number:
Molecular Weight:
259.17
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
215-981-2
MDL number:
Beilstein/REAXYS Number:
3707471
Assay:
>98%
Form:
solid
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Product Name

N-(1-Naphthyl)ethylenediamine dihydrochloride, ACS reagent, >98%

InChI key

MZNYWPRCVDMOJG-UHFFFAOYSA-N

InChI

1S/C12H14N2.2ClH/c13-8-9-14-12-7-3-5-10-4-1-2-6-11(10)12;;/h1-7,14H,8-9,13H2;2*1H

SMILES string

Cl.Cl.NCCNc1cccc2ccccc12

grade

ACS reagent

assay

>98%

form

solid

impurities

≤5% water

mp

194-198 °C (dec.) (lit.)

solubility

H2O: passes test

suitability

passes test for sensitivity to sulfanilamide

functional group

amine

Quality Level

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Application

N-(1-Naphthyl)ethylenediamine dihydrochloride has been used for the preparation of staining solution for the visualization of the reaction product(s) of starch active enzymes, containing α-1, 4 linked and α-1, 6 linked glucose by thin layer chromatography. It has also been used in modified Saville and Griess assays.
N-(1-Naphthyl)ethylenediamine dihydrochloride may be used in the synthesis of 5-[1,2]dithiolan-3-yl-pentanoic acid [2-(naphthalene-1-ylamino)-ethyl]amide (DPAN) by reacting with (±)-1,2-dithiolane-3-pentanoic acid in the presence of N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride and N-hydroxysuccinimide. The solution formed by dissolving N-(1-naphthyl)ethylenediamine dihydrochloride in sulfuric acid-methanol may be used as a reagent for the detection of sugars at nanoscale on thin-layer plates.
Coupling agent for the spectrophotometric determination of aminophenols, phenylenediamines, dinitroanilines, chloroanilines, thiols, and sulfonamides.
Solution of N-(1-naphthyl)ethylenediamine dihydrochloride in sulfuric acid-methanol may be employed for the quantitation of sugars.

General description

N-(1-Naphthyl)ethylenediamine dihydrochloride (NEDA·2HCl) acts as donor molecule and forms charge transfer (CT) complexes with π-acceptors (quinol and picric acid), σ-acceptors (iodine) and vacant orbital acceptors (tin(IV) tetrachloride and zinc chloride). These complexes were investigated by positron annihilation lifetime spectroscopy (PAL).

pictograms

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signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品
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Analytical Chemistry, 55, 1226-1226 (1983)
K K Verma et al.
Talanta, 38(3), 283-289 (1991-03-01)
A general assay procedure for a wide variety of thiols is described. The technique has three steps: (1) formation of S-nitrosothiols with nitrous acid, (2) destruction of the excess of nitrous acid, (3) hydrolysis of the S-nitrosothiols with mercuric ions
Product Analysis of Starch Active Enzymes by TLC.
Cockburn D and Koropatkin N.
Bio-protocol, 5(20) (2015)
N-(1-naphthyl)ethylenediamine dihydrochloride as a new reagent for nanomole quantification of sugars on thin-layer plates by a mathematical calibration process.
M Bounias
Analytical biochemistry, 106(2), 291-295 (1980-08-01)
Moamen S Refat et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 122, 34-47 (2013-12-03)
In this work, structural, thermal, morphological, pharmacological screening and positron annihilation lifetime measurements were performed on the interactions between a N-(1-Naphthyl)ethylenediamine dihydrochloride (NEDA·2HCl) donor and three types of acceptors to characterize these CT complexes. The three types of acceptors include

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