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16439

Sigma-Aldrich

β-tri-Calcium phosphate

≥95% β-phase basis (unsintered powder)

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Synonym(s):
β-TCP, β-Tricalcium phosphate
Empirical Formula (Hill Notation):
Ca3O8P2
CAS Number:
7758-87-4
Molecular Weight:
310.18
EC Number:
231-840-8
MDL number:
MFCD00015984
UNSPSC Code:
12352300
PubChem Substance ID:
329751238

Assay

≥95% β-phase basis (unsintered powder)

impurities

≤50 mg/kg total heavy metals (as lead)

anion traces

chloride (Cl-): ≤100 mg/kg
sulfur compounds (as SO42-): ≤250 mg/kg

cation traces

As: ≤0.5 mg/kg
Ba: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤10 mg/kg
Cu: ≤5 mg/kg
Hg: ≤0.5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤10 mg/kg
Zn: ≤10 mg/kg

InChI

1S/3Ca.2H3O4P/c;;;2*1-5(2,3)4/h;;;2*(H3,1,2,3,4)/q3*+2;;/p-6

InChI key

QORWJWZARLRLPR-UHFFFAOYSA-H

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Analysis Note

Phase Composition (by XRD analysis)
Low crystalinity Hydroxylapatite at unsintered condition.
A high crystalinity ß-Tricalcium phosphate after sintering at 1100C
ß-TCP: >95% ; Hydroxylapatite: <2.0% ; a-TCP: <1.0% TTCP: 0%
other Ca-P phases as Calcium pyrophosphate <2.0%

Other Notes

A -D suffix exists for administrative purposes only.
All -D packages are 100% the same product, same quality, same specification as the package sizes previously sold without a -D.

Regulatory Information

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Evaluation of hydroxyapatite and β-tri calcium phosphate microplasma spray coated pin intra-medullary for bone repair in a rabbit model.
Dey A, et al.
Ceramics International, 37(4), 1377-1391 (2011)
J Wiltfang et al.
Journal of biomedical materials research, 63(2), 115-121 (2002-03-01)
In seven Goettingen minipigs 3.5--4.7-ml cancellous bone defects were created in the area of the tibial head on both sides. The defects were filled with alpha-TCP or beta-TCP (tricalciumphosphate). ITI implants (Straumann, Freiburg, Germany) of 3.2 x 12-mm length were
Development of calcium phosphate based bioceramics.
Sinha A, et al.
Bulletin of Materials Science, 24(6), 653-657 (2001)
M Muschik et al.
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 10 Suppl 2, S178-S184 (2001-11-22)
The aim of this study is to evaluate the ability of beta-tricalcium phosphate (TCP) in granular form to achieve dorsal spondylodesis in adolescent idiopathic scoliosis (AIS). Twenty-eight patients underwent surgical correction and were followed up for 13+/-8 (range 6-33) months.
Timo Brandenburger et al.
Shock (Augusta, Ga.), 42(3), 234-238 (2014-07-01)
Remote ischemic preconditioning (RIPC) is an easily applicable method for protecting the heart against a subsequent ischemia and reperfusion (I/R) injury. However, the exact molecular mechanisms underlying RIPC are unknown. We examined the involvement of microRNAs (miRNAs) and in particular
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