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Tartrazine

analytical standard

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Synonym(s):
Acid Yellow 23
Empirical Formula (Hill Notation):
C16H9N4Na3O9S2
CAS Number:
1934-21-0
Molecular Weight:
534.36
Colour Index Number:
19140
Beilstein:
69850
EC Number:
217-699-5
MDL number:
MFCD00148908
UNSPSC Code:
85151701
PubChem Substance ID:
329747588
E Number:
E102
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥97.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

SMILES string

[Na+].[Na+].[Na+].[O-]C(=O)C1=NN(c2ccc(cc2)S([O-])(=O)=O)C(=O)C1N=Nc3ccc(cc3)S([O-])(=O)=O

InChI

1S/C16H12N4O9S2.3Na/c21-15-13(18-17-9-1-5-11(6-2-9)30(24,25)26)14(16(22)23)19-20(15)10-3-7-12(8-4-10)31(27,28)29;;;/h1-8,13H,(H,22,23)(H,24,25,26)(H,27,28,29);;;/q;3*+1/p-3

InChI key

UJMBCXLDXJUMFB-UHFFFAOYSA-K

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General description

Tartrazine is a synthetic azo dye, commonly found in drugs, food products and cosmetics. It can be synthesized by the reaction of sulfanilic acid with 3-carboxy-l-(4-sulfophenyl)-5-pyrazolone.

Application

Tartrazine may be used as reference standard for the determination of tartrazine in commercial soft drinks using thin layer chromatography and ion-pair high performance liquid chromatography.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Determination of synthetic food dyes in commercial soft drinks by TLC and ion-pair HPLC.
Andrade DIF, et al.
Food Chemistry, 157(8), 193-198 (2014)
Simultaneous analysis of tartrazine and its intermediates by reversed phase liquid chromatography.
Wittmer PD, et al.
Am. Fam. Physician., 47(8), 1422-1423 (1975)
Soheila Kashanian et al.
DNA and cell biology, 30(7), 499-505 (2011-04-12)
The interaction of native calf thymus DNA with tartrazine in 10 mM Tris-HCl aqueous solution at neutral pH 7.4 was investigated. Tartrazine is a nitrous derivative and may cause allergic reactions, with a potential of toxicological risk. Also, tartrazine induces oxidative
Helen Waechter et al.
Analytical chemistry, 83(7), 2719-2725 (2011-03-02)
We demonstrate a method for measuring optical loss simultaneously at multiple wavelengths with cavity ring-down spectroscopy (CRD). Phase-shift CRD spectroscopy is used to obtain the absorption of a sample from the phase lag of intensity modulated light that is entering
News from the Biological Stain Commission no. 6.
H O Lyon et al.
Biotechnic & histochemistry : official publication of the Biological Stain Commission, 85(2), 149-151 (2010-03-10)
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