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80717

Supelco

Brilliant Blue FCF

analytical standard

Synonym(s):

Erioglaucine disodium salt, E133, Acid Blue 9, Alphazurine FG, FD&C;BLUE No. 1

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About This Item

Empirical Formula (Hill Notation):
C37H34Na2N2O9S3
CAS Number:
3844-45-9
Molecular Weight:
792.85
Colour Index Number:
42090
EC Number:
223-339-8
MDL number:
MFCD00012141
UNSPSC Code:
85151701
PubChem Substance ID:
329769043
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥97.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

283 °C (dec.) (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

SMILES string

[Na+].[Na+].CCN(Cc1cccc(c1)S([O-])(=O)=O)c2ccc(cc2)C(=C3\C=C/C(C=C3)=[N+](\CC)Cc4cccc(c4)S([O-])(=O)=O)\c5ccccc5S([O-])(=O)=O

InChI

1S/C37H36N2O9S3.2Na/c1-3-38(25-27-9-7-11-33(23-27)49(40,41)42)31-19-15-29(16-20-31)37(35-13-5-6-14-36(35)51(46,47)48)30-17-21-32(22-18-30)39(4-2)26-28-10-8-12-34(24-28)50(43,44)45;;/h5-24H,3-4,25-26H2,1-2H3,(H2-,40,41,42,43,44,45,46,47,48);;/q;2*+1/p-2

InChI key

SGHZXLIDFTYFHQ-UHFFFAOYSA-L

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General description

Brilliant Blue FCF is a triarylmethane dye that is either used as a food or textile colorant to give blue color. An acceptable daily intake (ADI) of 12.0 mg/(kg body weight) was set for Brilliant Blue FCF in humans by the U.S. Food and Drug Administration (FDA).

Application

The analytical standards can also be used as follows:
  • Spectrophotometric quantitative estimation of Brilliant Blue, Sunset Yellow, Ponceau 4R, and Tartrazin from juice samples, using a transparent polymer matrix for extraction
  • Liquid-liquid microextraction of five synthetic food dyes from different food samples for their determination by high-performance liquid chromatography with a variable wavelength ultraviolet detector (HPLC-VWUVD)
  • Simultaneous analysis of five water-soluble synthetic colorants in different food samples by on-plate solid-phase extraction and thin-layer chromatography (TLC) with backlight-assisted detection
  • Multi-residue determination of 11 synthetic color food additives in high protein and fat content food products by HPLC combined with a diode array detector (DAD) or a tandem mass spectrometer (MS/MS)
  • Extraction of eight synthetic food dyes from 30 food samples of six types using an NH2-aminopropyl-modified silica SPE cartridge for their quantification by RP-HPLC coupled with UV detector

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

WGK

WGK 3

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Dafni Hadjieconomou et al.
Nature, 587(7834), 455-459 (2020-10-30)
Reproduction induces increased food intake across females of many animal species1-4, providing a physiologically relevant paradigm for the exploration of appetite regulation. Here, by examining the diversity of enteric neurons in Drosophila melanogaster, we identify a key role for gut-innervating
Qi Wu et al.
iScience, 23(1), 100776-100776 (2020-01-07)
Longitudinal measurements of food intake remain a challenge in Drosophila studies of nutrition and behavior. Here, we report an improved method for measuring fly food intake using dye-labeled food and excreta quantification (EX-Q). Reducing the surface area of the medium
Benjamin Ziman et al.
Journal of cell science, 133(10) (2020-04-09)
Nutrient availability upon feeding leads to an increase in body size in the planarian Schmidtea mediterranea However, it remains unclear how food consumption integrates with cell division at the organismal level. Here, we show that the NAD-dependent protein deacetylases sirtuins
Developmental toxicity assessment of common excipients using a stem cell-based in vitro morphogenesis model.
Yuan J C and Marikawa Y.
Food And Chemical Toxicology, 109, 376-385 (2017)
Christopher Kesten et al.
The EMBO journal, 38(24), e101822-e101822 (2019-11-19)
Environmental adaptation of organisms relies on fast perception and response to external signals, which lead to developmental changes. Plant cell growth is strongly dependent on cell wall remodeling. However, little is known about cell wall-related sensing of biotic stimuli and
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