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Merck
CN

AP132F

Goat Anti-Rabbit IgG Antibody, FITC conjugate

2 mg/mL, Chemicon®

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.46

Key Documents

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biological source

goat

Quality Level

100

conjugate

FITC conjugate

antibody form

affinity purified immunoglobulin

antibody product type

secondary antibodies

clone

polyclonal

species reactivity

rabbit

manufacturer/tradename

Chemicon®

concentration

2 mg/mL

technique(s)

immunofluorescence: suitable

shipped in

wet ice

target post-translational modification

unmodified

Related Categories

General description

Immunoglobulin G (IgG), is one of the most abundant proteins in human serum with normal levels between 8-17 mg/mL in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.

Application

Goat anti-Rabbit IgG Antibody, FITC conjugate is an antibody against Rabbit IgG for use in IF.

Biochem/physiol Actions

Reacts with Rabbit IgG gamma chain, as well as the light chains from all Rabbit immunoglobulin classes. Monospecific by IEP when tested against whole Rabbit serum.

FLUOROPHORE/PROTEIN:

Approximately 12 mg/mg.

Physical form

Reconstitute in 1 mL of sterile distilled water.

Preparation Note

that the concentration of protein and buffer salts will decrease to one-half of the original after

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302 + H312 + H332,H412

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sean McCutcheon et al.
Cell adhesion & migration, 11(1), 1-12 (2016-01-09)
Central nervous system (CNS) cells cultured in vitro as neuroclusters are useful models of tissue regeneration and disease progression. However, the role of cluster formation and collective migration of these neuroclusters to external stimuli has been largely unstudied in vitro.
Danit Mechlovich et al.
The Journal of pharmacology and experimental therapeutics, 333(3), 874-882 (2010-03-20)
Increasing evidence suggests that oxidative stress (OS)-induced pancreatic beta-cell impairments is involved in diabetes and diabetic complications. Our group has recently synthesized two multifunctional nontoxic, lipophilic, iron-chelating drugs, 5-{N-methyl-N-propargylaminomethyl}-8-hydroxyquinoline (M30) and 5-{4-propargylpiperazin-1-ylmethyl}-8-hydroxyquinoline (HLA20), for the treatment of various OS-mediated pathogeneses.
Sangkyu Park et al.
Cell proliferation, 51(6), e12500-e12500 (2018-08-29)
The sonic hedgehog (Shh) signalling pathway has an important role in the maintenance of various stem cells and organogenesis during development. However, the effect of Shh in skin-derived precursors (SKPs), which have the capacity for multipotency and self-renewal, is not
Huayang Wang et al.
Oncoimmunology, 5(4), e1122157-e1122157 (2016-05-04)
Tumor-infiltrated macrophages were potential targets of the immune therapy for patients with colon cancer. Colony stimulating factor 1 (CSF1) is a primary chemoattractant and functional regulator for macrophages, and therefore would be a feasible intervention for the macrophage-targeting therapeutics. However
Jennifer Rico-Varela et al.
Cellular and molecular bioengineering, 8(4), 553-565 (2015-11-26)
Medulloblastoma (MB) is a malignant pediatric brain tumor known for its aggressive metastatic potential. Despite the well-documented migration of MB cells to other parts of the brain and spinal column, MB chemotaxis is poorly understood. Herein, we examined the in
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