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Merck
CN

B1253

Sigma-Aldrich

Butylated hydroxyanisole

≥98.5%

Synonym(s):

2(3)-t-Butyl-4-hydroxyanisole, 2(3)-t-Butylhydroquinone monomethyl ether, BHA

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100 ML
¥211.05
500 ML
¥665.04
6 X 500 ML
¥2,434.10
24 X 500 ML
¥11,932.77

¥211.05


Available to ship on2025年4月14日Details


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100 ML
¥211.05
500 ML
¥665.04
6 X 500 ML
¥2,434.10
24 X 500 ML
¥11,932.77

About This Item

Linear Formula:
(CH3)3CC6H3(OCH3)OH
CAS Number:
Molecular Weight:
180.24
EC Number:
MDL number:
UNSPSC Code:
12352100
NACRES:
NA.22

¥211.05


Available to ship on2025年4月14日Details


Request a Bulk Order

vapor density

6.2 (vs air)

Assay

≥98.5%

form

powder

autoignition temp.

599 °F

mp

58-60 °C (lit.)

SMILES string

O(C)c1cc(c(cc1)O)C(C)(C)C

InChI

1S/C11H16O2/c1-11(2,3)9-7-8(13-4)5-6-10(9)12/h5-7,12H,1-4H3

InChI key

MRBKEAMVRSLQPH-UHFFFAOYSA-N

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This Item
PHR1419V900220100684
shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

shelf life

-

composition

acetic acid (30%), 1000 mL

composition

-

composition

-

composition

-

technique(s)

microbe id | metabolite detection: suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

application(s)

agriculture
clinical testing
environmental
food and beverages
pharmaceutical

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

-

suitability

Enterobacter spp.

suitability

-

suitability

-

suitability

-

General description

Butylated hydroxyanisole is mainly used as a synthetic antioxidant in food and cosmetics. It is being extensively studied for potential toxicity.[1][2]

Application

  • Antioxidant peptides from silk protein: Research explores the purification of novel antioxidant peptides derived from Bombyx mori pupae, identifying potential antioxidant applications for butylated hydroxyanisole in the food and cosmetic industries (Chukiatsiri et al., 2024).
  • Industrial lubricant additive: The performance of olive oil-based blended esters with butylated hydroxyanisole is evaluated, showcasing its efficacy as an industrial lubricant additive and its optimization using response surface methodology (Thangaraj et al., 2024).
  • Environmental degradation studies: Investigates the degradation of butylated hydroxyanisole using advanced oxidation processes, providing insights into environmental safety and the compound′s stability in pharmaceutical and industrial applications (Shi et al., 2024).

Other Notes

Mixed isomers (minimum 90% 3-isomer/9% 2-isomer)

Pictograms

Environment

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Chronic 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

241.9 °F - Pensky-Martens closed cup

Flash Point(C)

116.6 °C - Pensky-Martens closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Cytotoxicity of butylated hydroxyanisole and butylated hydroxytoluene in isolated rat hepatocytes
Thompson, David and Moldeus, Peter
Biochemical Pharmacology, 37(11), 2201-2207 (1988)
Toxicology and biochemistry of butylated hydroxyanisole and butylated hydroxytoluene.
A L Branen
Journal of the American Oil Chemists' Society, 52(2), 59-63 (1975-02-01)
Stefanie D Roth et al.
PloS one, 7(9), e44505-e44505 (2012-09-14)
Inefficient intracellular protein trafficking is a critical issue in the pathogenesis of a variety of diseases and in recombinant protein production. Here we investigated the trafficking of factor VIII (FVIII), which is affected in the coagulation disorder hemophilia A. We
Behrouz Hassannia et al.
The Journal of clinical investigation, 128(8), 3341-3355 (2018-06-26)
High-risk neuroblastoma is a devastating malignancy with very limited therapeutic options. Here, we identify withaferin A (WA) as a natural ferroptosis-inducing agent in neuroblastoma, which acts through a novel double-edged mechanism. WA dose-dependently either activates the nuclear factor-like 2 pathway
Yann Malato et al.
Gastroenterology, 143(6), 1597-1608 (2012-08-28)
The transcription factor nuclear factor κB (NF-κB) is activated by the IκB kinase complex. The regulatory subunit of this complex, NF-κB essential modifier (NEMO or IKBKG), is a tumor suppressor. Hepatocyte-specific deletion of NEMO induces chronic liver inflammation that leads

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