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Resomer^® RG 504 H, Poly(D,L-lactide-co-glycolide)

Name: Resomer<SUP>®</SUP> RG 504 H, Poly(<SC>D,L</SC>-lactide-<I>co</I>-glycolide)
Brand: ALDRICH

acid terminated, lactide:glycolide 50:50, M_w 38,000-54,000

Synonym(s):

PLGA

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About This Item

Linear Formula:

[C₃H₄O₂]_x[C₂H₂O₂]_y

CAS Number:

26780-50-7

UNSPSC Code:

12162002

NACRES:

NA.23

Quality Level

200

form

amorphous

feed ratio

lactide:glycolide 50:50

mol wt

M_w 38,000-54,000

degradation timeframe

<3 months

viscosity

0.45-0.60 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)

transition temp

T_g 46-50 °C

storage temp.

2-8°C

InChI

1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2

InChI key

LCSKNASZPVZHEG-UHFFFAOYSA-N

Related Categories

Biomedical Polymers

Application

Resomer^® RG 504 H, Poly(D, L-Lactide-co-Glycolide) can be used to fabricate a biodegradable hemostyptic device for safe and locally controlled release of thrombin which promotes local blood clot formation.

It can be used to preparepolymer nanospheres for encapsulating CuO, to form stimuli-responsivemultifunctional nanocarriers.

Legal Information

Product of Evonik

RESOMER is a registered trademark of Evonik Rohm GmbH

related product

Product No.

Description

Pricing

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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An in situ forming gel (ISFG) of buprenorphine (BP) was prepared using PLGA-PEG-PLGA (triblock) and N‑methyl‑2‑pyrrolidone as solvent for decreasing the initial burst release. Supercritical CO2 method was used for ring opening polymerization of triblock. The optimum formulation of ISFG

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