Skip to Content
Merck
CN
All Photos(2)

Documents

Safety Information

912212

Sigma-Aldrich

NanoFabTx PLGA-micro

for synthesis of 10-30 um particles

Sign Into View Organizational & Contract Pricing

Synonym(s):
NanoFabTx reagent kit, PLGA microparticle kit
UNSPSC Code:
12161503
NACRES:
NA.23

Quality Level

application(s)

advanced drug delivery

storage temp.

2-8°C

Looking for similar products? Visit Product Comparison Guide

General description

NanoFabTx PLGA-micro for synthesis of 10-30 μm particle reagent kit is a formulation kit that includes the reagents, stabilizers, and protocol to synthesize poly(lactic-co-glycolic acid) (PLGA) microparticles 10-30 μm in size. This reagent kit can be used with the NanoFabTx Microfluidic - micro device kit (Cat.No. 911879).

Application

This NanoFabTx reagent kit is designed for the synthesis of 10-30 μm PLGA microparticles to encapsulate a wide variety of therapeutic drug molecules for targeted drug delivery. By following the protocol, the user can synthesize drug-encapsulating microspheres 10 μm in size, 30 μm in size, or any size in between. With our step-by-step instructions, the user can identify the ideal microparticle size and drug loading for their research application without the need for lengthy trial-and-error optimization. PLGA microparticles are an excellent drug delivery system for controlled drug release because microparticles offer better encapsulation efficiency including higher drug loading capacity and lower excipient loads than nanoparticles. PLGA is a biocompatible and biodegradable polymer and compatible with many different types of therapeutic molecules and is the most widely used synthetic polymer in precision oncology. PLGA is approved by the FDA for biomedical and pharmaceutical applications such as oncology and immuno-oncology.

Features and Benefits

  • Step-by-step protocols developed and tested by our formulation scientists
  • Flexible synthesis tool to create uniform and reproducible microparticles with low polydispersity
  • Based on non-toxic, biodegradable polymers
  • Enables microparticle formulation screening and optimization to select ideal particle size for enhanced drug loading and controlled release

Legal Information

NANOFABTX is a trademark of Sigma-Aldrich Co. LLC

WGK

WGK 3

Regulatory Information

新产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

NanoFabTx™ platform accelerates drug development with ready-to-use formulations and microfluidic devices for particle synthesis.

NanoFabTX drug delivery formulation kits and lipids mixes for mRNA, nucleic acid, and small molecule delivery in lipid nanoparticles, liposomes and polymeric nanoparticles prepared using Precision NanoSystems microfluidic NanoAssemblr

Professor Robert K. Prud’homme introduces flash nanoprecipitation (FNP) for nanoparticle fabrication, which is a scalable, rapid mixing process for nanoparticle formulations.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service