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Sigma-Aldrich

Decamethylcyclopentasiloxane

97%

Synonym(s):

2,2,4,4,6,6,8,8,10,10-Decamethylcyclopentasiloxane, Cyclic dimethylsiloxane pentamer, Cyclo-decamethylpentasiloxane, Cyclomethicone pentamer 245, Decamethylpentacyclosiloxane

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About This Item

Empirical Formula (Hill Notation):
C10H30O5Si5
CAS Number:
541-02-6
Molecular Weight:
370.77
Beilstein:
1800166
EC Number:
208-764-9
MDL number:
MFCD00046966
UNSPSC Code:
12352103
PubChem Substance ID:
24868110
NACRES:
NA.22

Quality Level

100

Assay

97%

form

liquid

refractive index

n20/D 1.396 (lit.)

bp

90 °C/10 mmHg (lit.)

density

0.958 g/mL at 25 °C (lit.)

SMILES string

C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1

InChI

1S/C10H30O5Si5/c1-16(2)11-17(3,4)13-19(7,8)15-20(9,10)14-18(5,6)12-16/h1-10H3

InChI key

XMSXQFUHVRWGNA-UHFFFAOYSA-N

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General description

Decamethylcyclopentasiloxane (D5) is used in personal care products including skin creams, cosmetics, shampoos, deodorants and conditioners. D5 is also used in various applications such as industrial cleaning fluids and dry cleaning solvents.

Application

Decamethylcyclopentasiloxane (D5) can be used as:
  • A greener solvent in synthetic chemistry applications.
  • A monomeric unit for polymerization by various base catalysts to obtain polysiloxane polymer.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

163.4 °F - closed cup

Flash Point(C)

73 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Characterization of ecological risks from environmental releases of decamethylcyclopentasiloxane (D5).
Fairbrother A, et al.
Environmental Toxicology and Chemistry / Setac, 34(12), 2715-2722 (2015)
Qiyan Li et al.
Cell biochemistry and function, 32(2), 183-187 (2013-09-03)
Corneal epithelial barrier dysfunction is harmful to corneal health; the pathogenesis is unclear. This study aims to elucidate the mechanism by which tryptase compromises corneal epithelial barrier function. Human corneal epithelial cell line (HCE cells) was cultured into monolayers using
Ring-opening polymerization of decamethylcyclopentasiloxane initiated by a superbase: Kinetics and rheology.
Pibre G, et al.
Polymer, 49(1), 234-240 (2008)
Vivian C Chioma et al.
Biological psychiatry, 89(10), 947-958 (2021-02-14)
Seeking addictive drugs is regulated by synaptic plasticity in the nucleus accumbens core and involves distinct plasticity in D1 and D2 receptor-expressing medium spiny neurons (D1/2-MSNs). However, it is unknown how differential plasticity between the two cell types is coordinated.
Zhongwang Yu et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 9(24), e2105442-e2105442 (2022-06-28)
Blood-brain barrier (BBB) impairment is an early prevalent feature of multiple sclerosis (MS), and remains vital for MS progression. Microglial activation precedes BBB disruption and cellular infiltrates in the brain of MS patients. However, little is known about the function
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