Skip to Content
Merck
CN
All Photos(1)

Documents

Safety Information

440655

Sigma-Aldrich

Boc-Asp(OBzl)-OH

98%

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
N-(tert-Butoxycarbonyl)-L-aspartic acid 4-benzyl ester, Boc-L-aspartic acid 4-benzyl ester
Linear Formula:
C6H5CH2OCOCH2CH(COOH)NHCOOC(CH3)3
CAS Number:
7536-58-5
Molecular Weight:
323.34
Beilstein:
2064127
EC Number:
231-406-8
MDL number:
MFCD00065564
UNSPSC Code:
12352200
PubChem Substance ID:
24867616

Assay

98%

optical activity

[α]20/D −19.5°, c = 2 in DMF

mp

98-102 °C (lit.)

SMILES string

[H][C@@](CC(=O)OCc1ccccc1)(NC(=O)OC(C)(C)C)C(O)=O

InChI

1S/C16H21NO6/c1-16(2,3)23-15(21)17-12(14(19)20)9-13(18)22-10-11-7-5-4-6-8-11/h4-8,12H,9-10H2,1-3H3,(H,17,21)(H,19,20)/t12-/m0/s1

InChI key

SOHLZANWVLCPHK-LBPRGKRZSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Starting material for the enantiospecific synthesis of (R)-(+)-Boc-iturinic acid (n-C14), the L-aspartic series of thrombin inhibitors, and diketopiperazine tetrapeptides. Used in the preparation of a novel tricyclic dipeptide mimetic based on a [6H]-azepino indoline nucleus.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

新产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

De Lombaert, S. et al.
Tetrahedron Letters, 35, 7513-7513 (1994)
Bergeron, R.J. et al.
Journal of the American Chemical Society, 116, 8479-8479 (1994)
K Hilpert et al.
Journal of medicinal chemistry, 37(23), 3889-3901 (1994-11-11)
Thrombin, a serine protease, plays a central role in the initiation and propagation of thrombotic events. An extensive search for new thrombin inhibitors was performed, using an unconventional approach. Screening of small basic molecules for binding in the recognition pocket
Vitamin K1 dependent carboxylase: beta-carboxylation of t-butyloxycarbonylaspartic acid alpha-benzyl ester.
S E Hamilton et al.
Biochemical and biophysical research communications, 107(1), 246-249 (1982-07-16)
Bland, J.M.
Synthetic Communications, 25, 467-467 (1995)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service