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440167

Sigma-Aldrich

(3-Glycidyloxypropyl)trimethoxysilane

≥98%

Synonym(s):

3-(2,3-Epoxypropoxy)propyltrimethoxysilane, GLYMO, Glycidyl 3-(trimethoxysilyl)propyl ether

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25 MG
CN¥4,549.28
100 MG
CN¥11,969.92

CN¥4,549.28

Estimated to ship onApril 07, 2025Details

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25 MG
CN¥4,549.28
100 MG
CN¥11,969.92

About This Item

Empirical Formula (Hill Notation):
C9H20O5Si
CAS Number:
2530-83-8
Molecular Weight:
236.34
Beilstein:
4308125
EC Number:
219-784-2
MDL number:
MFCD00005144
UNSPSC Code:
12352103
PubChem Substance ID:
24867573
NACRES:
NA.23

CN¥4,549.28

Estimated to ship onApril 07, 2025Details

Request a Bulk Order

Quality Level

200

Assay

≥98%

form

liquid

refractive index

n20/D 1.429 (lit.)

bp

120 °C/2 mmHg (lit.)

density

1.07 g/mL at 25 °C (lit.)

SMILES string

CO[Si](CCCOCC1CO1)(OC)OC

InChI

1S/C9H20O5Si/c1-10-15(11-2,12-3)6-4-5-13-7-9-8-14-9/h9H,4-8H2,1-3H3

InChI key

BPSIOYPQMFLKFR-UHFFFAOYSA-N

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5(6)-Carboxyfluorescein

5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate BioReagent, suitable for fluorescence, ≥85% (HPCE)

21884

5(6)-Carboxy-2′,7′-dichlorofluorescein diacetate

fluorescence

λex 492 nm; λem 517 nm in 0.1 M Tris pH 8.0 (esterase)

fluorescence

λex 492 nm; λem 517 nm in DMF

fluorescence

λex 492 nm; λem 517 nm in 0.1 M Tris pH 8.0

fluorescence

λex 470 nm; λem 529 nm in 0.1 M Tris pH 8.0 (esterase)

solubility

DMF: soluble, DMSO: soluble

solubility

DMF: soluble, DMSO: soluble

solubility

-

solubility

DMF: soluble, DMSO: soluble, methanol: soluble

form

solid

form

powder

form

powder

form

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

-

storage temp.

−20°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

General description

(3-Glycidyloxypropyl)trimethoxysilane (GPTMS) is a bifunctional organosilane with three methoxy groups on one side and an epoxy ring on the other. The methoxy groups bind well with glass substrates creating a 3D matrix. The epoxy group is reactive with amides, alcohols, thiols and acids. GPTMS is highly reactive in water and can be used as a linking agent between the surface of the silica and the polymeric matrix.[1][2][3]

Application

GPTMS is widely used as a silica precursor. GPTMS alone with tetraethylortosilicate (TEOS) can be blended with chitosan for use as a filler for polymeric scaffold for bone tissue engineering.[4] It can also be coated on the surface of aluminium alloy to protect from corrosion.[5] GPTMS can used to functionalize (wrap) multi-walled carbon nanotubes (MWCNTs) which can be used as s a reinforcement in epoxy matrix nanocomposites.[2]
Pre-treatment of carbon steel with 3-(Glycidoxypropyl)trimethoxysilane enhances the dry and wet adhesion while reducing the cathotic disbondment rate of an epoxy coating[6]

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H318,H412

Hazard Classifications

Aquatic Chronic 3 - Eye Dam. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
  • Specification Sheet

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    SDBB1794
    SDBB1793
    SDBB0475
    STBL0642
    STBL2731

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    1. Which document(s) contains shelf-life or expiration date information for a given product?

      If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

    2. How do I get lot-specific information or a Certificate of Analysis?

      The lot specific COA document can be found by entering the lot number above under the "Documents" section.

    3. Is Product 440167 (3-Glycidyloxypropyl)trimethoxysilane GLYMO, equivalent to Dow's Z-6040?

      Yes. This listing is manufactured by Dow Corning Corporation and distributed by Sigma-Aldrich.

    4. What can Product 440167, 3-Glycidyloxypropyl)trimethoxysilane GLYMO, be used for?

      According to Dow Corning®, 3-GLYCIDOXYPROPYLTRIMETHOXYSILANE can be used as a coupling agent for many thermoset resins with glass or  mineral fillers. Specifically, it has been used as a reinforcement treatment on glass fiber to improve physical properties (especially wet strength) or as  an adhesion promoter to improve the bonding of a polymer coating or adhesive to glass, metals or other polymeric surfaces.

    5. What is the viscosity of Product 440167 (3-Glycidyloxypropyl)trimethoxysilane GLYMO?

      This material is a low viscosity liquid with an average value of about 3 centistokes. Please note that this value is not part of our specifications.

    6. Where can I find more detailed information about how to use Product 440167. 3-Glycidyloxypropyl)trimethoxysilane, GLYMO, in adhesion/reinforcement applications?

      Dow Corning® has published a technical bulletin on this product, which is available by calling Technical Service at 800-231-8327.

    7. How do I find price and availability?

      There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

    8. What is the Department of Transportation shipping information for this product?

      Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

    9. My question is not addressed here, how can I contact Technical Service for assistance?

      Ask a Scientist here.

    Jadra Mosa et al.
    Membranes, 9(9) (2019-08-30)
    Organic/inorganic hybrid membranes that are based on GTT (GPTMS-TMES-TPTE) system while using 3-Glycidoxypropyl-trimethoxysilane (GPTMS), Trimethyletoxisilane (TMES), and Trimethylolpropane triglycidyl ether (TPTE) as precursors have been obtained while using a combination of organic polymerization and sol-gel synthesis to be used as
    Functionalization of carbon nanotubes with (3-glycidyloxypropyl)-trimethoxysilane: Effect of wrapping on epoxy matrix nanocomposites.
    Hoepfner, et al.
    Journal of Applied Polymer Science, 133(47), 814-820 (2016)
    Ngoc-Hanh Cao-Luu et al.
    Journal of colloid and interface science, 536, 536-547 (2018-11-06)
    How to encapsulate poly(N-isopropylacrylamide) (PNIPAM) mesoglobule cores by silica shells greatly affects the resultant nanoparticle structures. Incorporation of acrylamide (AM) unit into PNIPAM in combination with 3-glycidyloxypropyltrimethoxysilane (GLYMO, as a coupling agent) effectively induces nucleation and growth of silica on
    An assessment of the corrosion protection of AA2024-T3 treated with vinyltrimethoxysilane/(3-glycidyloxypropyl) trimethoxysilane.
    Dalmoro V et al.
    Corrosion Science, 92(19), 200-208 (2015)
    Giulia Giuntoli et al.
    Frontiers in bioengineering and biotechnology, 8, 589223-589223 (2021-02-09)
    Abdominal hernia repair is a frequently performed surgical procedure worldwide. Currently, the use of polypropylene (PP) surgical meshes for the repair of abdominal hernias constitutes the primary surgical approach, being widely accepted as superior to primary suture repair. Surgical meshes
    View All Related Papers

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