378909
Ethyl 3-hydrazino-3-oxopropionate
97%
Synonym(s):
Ethyl malonyl hydrazide
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Linear Formula:
H2NNHCOCH2CO2C2H5
CAS Number:
Molecular Weight:
146.14
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Assay
97%
form
solid
mp
72-75 °C (lit.)
functional group
amine
ester
hydrazine
SMILES string
CCOC(=O)CC(=O)NN
InChI
1S/C5H10N2O3/c1-2-10-5(9)3-4(8)7-6/h2-3,6H2,1H3,(H,7,8)
InChI key
HCPOCMMGKBZWSJ-UHFFFAOYSA-N
Application
Ethyl 3-hydrazino-3-oxopropionate may be used in the following studies:
- As starting reagent in the step-wise construction of complex pyrrole-pyrazole system.,
- Synthesis of 4,5-dihydro-1H-pyrazoles, via reaction with 4-alkoxy-1,1,1-trifluoro-3-alken-2-ones, using conventional thermal heating method and a microwave-assisted method.
- Synthesis of pyrazolopyridazine.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
新产品
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Sequential Construction of Complex Pyrrole-Pyrrole or Pyrrole-Pyrazole Systems from 1, 2-Diaza-1, 3-butadienes.
Attanasi OA, et al.
Synlett, 09, 1367-1370 (1999)
Miguel F Braña et al.
Journal of medicinal chemistry, 48(22), 6843-6854 (2005-10-28)
Pyrazolopyridazine 1a was identified in a high-throughput screening carried out by BASF Bioresearch Corp. (Worcester, MA) as a potent inhibitor of CDK1/cyclin B and shown to have selectivity for the CDK family. Analogues of the lead compound have been synthesized
Regioselective role of the hydrazide moiety in the formation of complex pyrrole-pyrazole systems
Attanasi OA, et al.
Tetrahedron, 57(7), 1387-1394 (2001)
An E-factor minimized solvent-free protocol for the preparation of 4, 5-dihydro-5-(trifluoromethyl)-1H-pyrazoles.
Buriol L, et al.
Monatshefte fur Chemie / Chemical Monthly, 142(5), 515-520 (2011)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service