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Sigma-Aldrich

(Aminomethyl)phosphonic acid

99%

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Synonym(s):
AMPA
Linear Formula:
NH2CH2P(O)(OH)2
CAS Number:
1066-51-9
Molecular Weight:
111.04
Beilstein:
1701219
MDL number:
MFCD00008105
UNSPSC Code:
12352100
PubChem Substance ID:
24859469
NACRES:
NA.22

Quality Level

100

Assay

99%

form

solid

solubility

water: soluble 50 mg/mL, clear, colorless

SMILES string

NCP(O)(O)=O

InChI

1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)

InChI key

MGRVRXRGTBOSHW-UHFFFAOYSA-N

Gene Information

human ... F10(2159) , F2(2147) , PLG(5340)
rat ... Gria1(50592) , Gria2(29627) , Gria3(29628) , Gria4(29629) , Grik1(29559) , Grik2(54257) , Grin2a(24409) , Grm1(24414) , Grm2(24415) , Grm4(24417) , Grm5(24418) , Slc1a1(25550) , Slc1a2(29482) , Slc1a3(29483)

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General description

(Aminomethyl)phosphonic acid is a metabolite of amitrole and glyphosate herbicides and was analyzed by HPLC using an electrochemical detector.

Application

(Aminomethyl)phosphonic acid was used to develop a novel kind of immobilized metal affinity chromatography column based on organic-inorganic hybrid silica monolith.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Chunyan Hou et al.
Journal of proteome research, 9(8), 4093-4101 (2010-06-24)
A novel kind of immobilized metal affinity chromatography (IMAC) column based on organic-inorganic hybrid silica monolith has been developed. The monolithic support was prepared in a 250 microm i.d. capillary by the sol-gel method with tetraethoxysilane (TEOS) and 3-aminopropyltriethoxysilane (APTES)
Francisco Sánchez-Bayo et al.
Analytica chimica acta, 675(2), 125-131 (2010-08-31)
The herbicides amitrole and glyphosate, and its metabolite aminomethyl-phosphonic acid (AMPA), in water samples have been directly analysed by high-performance liquid chromatography using an electrochemical (EC) detector. Limits of detection of 0.3 microg mL(-1) for glyphosate, 0.05 microg mL(-1) for
A S F Araújo et al.
Chemosphere, 52(5), 799-804 (2003-05-22)
Glyphosate [N-(phosphonomethyl)-glycine] is a broad-spectrum, non-selective, post-emergence herbicide that is widely used in agricultural. We studied, in vitro, changes in the microbial activity of typical Hapludult and Hapludox Brazilian soils, with and without applied glyphosate. Glyphosate was applied at a
Fabrizio Botta et al.
Chemosphere, 77(1), 133-139 (2009-06-02)
A study of glyphosate and aminomethyl phosphonic acid (AMPA) transfer in the Orge watershed (France) was carried out during 2007 and 2008. Water samples were collected in surface water, wastewater sewer, storm sewer and wastewater treatment plant (WWTP). These two
M Tomita et al.
Journal of chromatography, 571(1-2), 324-330 (1991-11-15)
Capillary electrophoresis has been used to separate and quantitate glyphosate and its major metabolite, (aminomethyl)phosphonic acid (AMPA), in serum. The two compounds, after derivatization with p-toluenesulphonyl chloride, were clearly separated with 0.1 M boric acid-sodium hydroxide buffer (pH 9.6) containing
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