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308633

Sigma-Aldrich

2-Hydroxyethyl cellulose

average Mw ~380,000

Synonym(s):

HEC

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1 MG
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CN¥2,574.65

Estimated to ship onMay 06, 2025Details

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1 MG
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About This Item

CAS Number:
9004-62-0
MDL number:
MFCD00072770
UNSPSC Code:
12162002
NACRES:
NA.23

CN¥2,574.65

Estimated to ship onMay 06, 2025Details

Request a Bulk Order

description

Viscosity:300 - 400 cps, c = 2%; Water at 25° C

form

powder

autoignition temp.

725 °F

mol wt

average Mw ~380,000

extent of labeling

1.0 mol per mol cellulose (D.S.)
2.0 mol per mol cellulose (M.S.)

mp

288-290 °C (dec.)

density

0.6 g/mL at 25 °C (lit.)

SMILES string

O1C(C(C(C(C1CO)OC)O)OCCO)OC2C(OC(C(C2O)O)OC4C(OC(C(C4O)O)C)CO)COC3OC(C(C(C3O)O)OC)CO

InChI

1S/C29H52O21/c1-10-15(34)16(35)24(13(8-33)45-10)49-28-20(39)18(37)25(50-29-26(43-5-4-30)21(40)23(42-3)12(7-32)47-29)14(48-28)9-44-27-19(38)17(36)22(41-2)11(6-31)46-27/h10-40H,4-9H2,1-3H3

InChI key

CWSZBVAUYPTXTG-UHFFFAOYSA-N

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General description

2-Hydroxyethyl cellulose (HEC) is a water soluble biopolymer that is majorly used as a thickener and an adhesive. It has water retention which also includes good film forming ability for protective covering.[1][2]
Non-ionic water soluble polymer. Aqueous solutions are pseudoplastic. Readily disperses without lumping.

Application

Thickener, protective colloid, binder, stabilizer and suspending agent.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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    Chemical modification of cellulose extracted from sugarcane bagasse: Preparation of hydroxyethyl cellulose
    Abdel-Halim ES
    Arabian Journal of Chemistry, 7(3), 362-371 (2014)
    Distribution of substituents in O-(2-hydroxyethyl) cellulose
    Lindberg B, et al.
    Carbohydrate Research, 170(2), 207-214 (1987)
    Prem N Gupta et al.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 46(5), 315-322 (2012-03-01)
    Mucosally-administered vaccine strategies are widely investigated as a promising means of preventing HIV infection. This study describes the development of liposomal gel formulations, and novel lyophilised variants, comprising HIV-1 envelope glycoprotein, CN54gp140, encapsulated within neutral, positively charged or negatively charged
    Maoqiang Xue et al.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 912, 1-7 (2013-01-08)
    Microporous anodic aluminum oxide (AAO) membranes were modified by 3-glycidoxypropyltrimethoxysilane to produce terminal epoxy groups. These were used to covalently link hydroxyethyl celluloses (HEC) to amplify reactive groups of AAO membrane. The hydroxyl groups of HEC-AAO composite membrane were further
    Ying-Chen Chen et al.
    International journal of pharmaceutics, 441(1-2), 162-169 (2012-12-15)
    The aim was to develop gastroretentive drug delivery systems (GRDDSs) by combining floating and swelling. GRDDS tablets formulated with hydroxyethylcellulose (HEC), chitosan (CS) and sodium bicarbonate (SB) for evaluating floating capacity (floating lag time and duration) and swelling characteristics. CS
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