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435007

Sigma-Aldrich

Hydroxypropyl cellulose

average Mw ~80,000, average Mn ~10,000, powder, 20 mesh particle size (99% through)

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Synonym(s):
HPC
CAS Number:
9004-64-2
MDL number:
MFCD00132688
UNSPSC Code:
12162002
NACRES:
NA.23

description

biological oxygen demand (BOD) 14,000 ppm

Quality Level

200

form

powder

autoignition temp.

752 °F

mol wt

average Mn ~10,000
average Mw ~80,000

impurities

<5 wt. %

particle size

20 mesh (99% through)

pH

5.0-8.5

interfacial tension mineral oil

12.5 dyn/cm, 0.1 wt. % in H2O (vs. mineral oil)

viscosity

250-800 cP, 10 wt. % in H2O(25 °C)(lit.)

solubility

H2O: insoluble (above 45 °C)
polar organic solvents: soluble

density

0.5 g/mL at 25 °C (lit.)

InChI

1S/C12H20N2/c1-5-12(13)11-7-6-10(14(3)4)8-9(11)2/h6-8,12H,5,13H2,1-4H3

InChI key

RRHXDYJWVYFMKV-UHFFFAOYSA-N

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General description

Hydroxypropyl cellulose (HPC) is biocompatible in nature and exhibits low critical solution temperature (LCST). It has been reported to be prepared by reacting cellulose with alkali, producing alkali cellulose which is consecutively reacted with propylene oxide. HPC is soluble in water at lower than RT. Viscosity behaves inversely to rise in temperature.

Application

Copolymers composed of HPC backbones with poly((2-dimethyl amino)ethyl methacrylate side chains has been synthesized for gene delivery. HPC has been used as a binder in to nanostructured anatase membranes. Polymer conjugates made of HPC backbones and poly(N-isopropylacryamide) as side chains act as smart hydrogels. HPC has been reported to be studied as a glue.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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A Study on Painting Layer Fixative Processing of Mural Paintings of Buddhist Temples in Korea
Lee HS, et al.
Journal of the Korean Conservation Science for Cultural Properties, 29(1), 81-93 (2013)
Synthesis of nanostructured anatase mesoporous membranes with photocatalytic and separation capabilities for water ultrafiltration process
Tajer-Kajinebaf V, et al.
International Journal of Photoenergy (2013)
F J Xu et al.
Bioconjugate chemistry, 20(8), 1449-1458 (2009-08-04)
Cationic polymers have been of interest and importance as nonviral gene delivery carriers. Herein, well-defined comb-shaped cationic copolymers (HPDs) composed of long biocompatible hydroxypropyl cellulose (or HPC) backbones and short poly((2-dimethyl amino)ethyl methacrylate) (or P(DMAEMA)) side chains were prepared as
Thomas E. Furia
CRC Handbook of Food Additives null
F J Xu et al.
Bioconjugate chemistry, 21(3), 456-464 (2010-02-25)
Hydroxypropyl cellulose (HPC) possesses a lower critical solution temperature (LCST) above 40 °C, while the poly(N-isopropylacrylamide) (P(NIPAAm)) exhibits a LCST of about 32 °C. Herein, comb-shaped copolymer conjugates of HPC backbones and low-molecular-weight P(NIPAAm) side chains (HPC-g-P(NIPAAm) or HPN) were
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