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Merck
CN

434965

2-Hydroxyethyl cellulose

average Mv ~90,000

Synonym(s):

Cellulose hydroxyethyl ether

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About This Item

CAS Number:
9004-62-0
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:
MFCD00072770

Key Documents

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Product Name

2-Hydroxyethyl cellulose, average Mv ~90,000

SMILES string

O1C(C(C(C(C1CO)OC)O)OCCO)OC2C(OC(C(C2O)O)OC4C(OC(C(C4O)O)C)CO)COC3OC(C(C(C3O)O)OC)CO

InChI

1S/C29H52O21/c1-10-15(34)16(35)24(13(8-33)45-10)49-28-20(39)18(37)25(50-29-26(43-5-4-30)21(40)23(42-3)12(7-32)47-29)14(48-28)9-44-27-19(38)17(36)22(41-2)11(6-31)46-27/h10-40H,4-9H2,1-3H3

InChI key

CWSZBVAUYPTXTG-UHFFFAOYSA-N

form

powder

autoignition temp.

725 °F

mol wt

average Mv ~90,000

extent of labeling

2.5 mol per mol cellulose (M.S.)

viscosity

100-180 cP(lit.)

density

0.6 g/mL at 25 °C (lit.)

Quality Level

100

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Related Categories

Application

Thickener, protective colloid, binder, stabilizer and suspending agent.

General description

2-Hydroxyethyl cellulose (HEC) is a water soluble biopolymer that is majorly used as a thickener and an adhesive. It has water retention properties and good film forming ability for protective covering.
Non-ionic water soluble polymer. Aqueous solutions are pseudoplastic. Readily disperses without lumping.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ9113
MKCX2499
MKCV5840
MKCV8391
MKCT9438

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Chemical modification of cellulose extracted from sugarcane bagasse: Preparation of hydroxyethyl cellulose
Abdel-Halim ES
Arabian Journal of Chemistry, 7(3), 362-371 (2014)
Distribution of substituents in O-(2-hydroxyethyl) cellulose
Lindberg B, et al.
Carbohydrate Research, 170(2), 207-214 (1987)
Prem N Gupta et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 46(5), 315-322 (2012-03-01)
Mucosally-administered vaccine strategies are widely investigated as a promising means of preventing HIV infection. This study describes the development of liposomal gel formulations, and novel lyophilised variants, comprising HIV-1 envelope glycoprotein, CN54gp140, encapsulated within neutral, positively charged or negatively charged
Maoqiang Xue et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 912, 1-7 (2013-01-08)
Microporous anodic aluminum oxide (AAO) membranes were modified by 3-glycidoxypropyltrimethoxysilane to produce terminal epoxy groups. These were used to covalently link hydroxyethyl celluloses (HEC) to amplify reactive groups of AAO membrane. The hydroxyl groups of HEC-AAO composite membrane were further
Ying-Chen Chen et al.
International journal of pharmaceutics, 441(1-2), 162-169 (2012-12-15)
The aim was to develop gastroretentive drug delivery systems (GRDDSs) by combining floating and swelling. GRDDS tablets formulated with hydroxyethylcellulose (HEC), chitosan (CS) and sodium bicarbonate (SB) for evaluating floating capacity (floating lag time and duration) and swelling characteristics. CS
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