biological source
rabbit
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
mouse, human
technique(s)
flow cytometry: suitable, immunocytochemistry: suitable, immunofluorescence: suitable, immunoprecipitation (IP): suitable, indirect ELISA: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CXCR4(7852)
General description
C-X-C基序趋化因子受体4 (CXCR4) 由位于人染色体2q22.1的基因编码。该基因编码具有七个跨膜区的蛋白质。编码的蛋白在T-细胞、B-细胞、单核细胞、嗜中性粒细胞和树突细胞表面表达。
Immunogen
CXCR4 抗体,该肽对应于人 CXCR4 氨基末端周围的氨基酸。
Biochem/physiol Actions
C-X-C基序趋化因子受体4(CXCR4)对基质细胞衍生因子-1具有特异性。它在调节各种免疫细胞类型的免疫反应中起着至关重要的作用。CXCR4与C4(分化簇4)相互作用,允许人类免疫缺陷病毒1型(HIV-1)进入并感染细胞。该基因中的多态性与少年特发性关节炎(JIA)的发展相关。此外,该基因的突变会增加患心血管疾病(CVD)的风险。
Features and Benefits
您可完全放心的评估我们的抗体。如果抗体在您的应用中没有发挥效果,我们将给予您完全的赔偿或更换抗体。 了解更多。
Physical form
以含有 0.02% 叠氮化钠的 PBS 形式提供。
Other Notes
可以使用阻断肽 SBP3500383 阻断该抗体的作用。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
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T Lai-Lei, et al.
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