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Merck
CN

761435

Sigma-Aldrich

[(二(1-金刚烷基)丁基膦基)-2-(2′-氨基-1,1′-联苯基)]钯(II)甲磺酸酯

95%

别名:

[(二(1-金刚烷基)丁基膦基)-2-(2′-氨基-1,1′-联苯基)]钯(II) 甲磺酸酯, cataCXium-A-Pd-G3, 甲磺酸[(二(1-金刚烷基)丁基膦基)-2-(2′-氨基-1,1′-联苯基)]钯(II)

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About This Item

经验公式(希尔记法):
C37H52NO3PPdS
分子量:
728.27
UNSPSC代码:
12352300
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

95%

形式

solid

特点

generation 3

反应适用性

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
reaction type: Cross Couplings

杂质

≤3% acetone

mp

196-241 °C (decomposition)

官能团

phosphine

SMILES字符串

CS(=O)(=O)O[Pd]c1ccccc1-c2ccccc2N.CCCCP([C@@]34C[C@@H]5C[C@@H](C[C@@H](C5)C3)C4)[C@@]67C[C@@H]8C[C@@H](C[C@@H](C8)C6)C7

InChI

1S/C24H39P.C12H10N.CH4O3S.Pd/c1-2-3-4-25(23-11-17-5-18(12-23)7-19(6-17)13-23)24-14-20-8-21(15-24)10-22(9-20)16-24;13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;1-5(2,3)4;/h17-22H,2-16H2,1H3;1-6,8-9H,13H2;1H3,(H,2,3,4);/q;;;+1/p-1/t17-,18+,19-,20-,21+,22-,23-,24-;;;

InChI key

REYVZCOGMIXVNX-DVBMAMJVSA-M

应用

cataCXium® A Pd G3 是一种第三代Buchwald预催化剂,可用于:
  • 吡啶羧酸的直接邻位芳基化。
  • 催化Suzuki–Miyaura交叉偶联反应,以合成1-杂芳基-3-氮杂双环[3.1.0]己烷。
  • 炔烃的钯催化羰基碳全氟烷基化。
  • 各种 gem二取代环丙烷的合成过程中成对二(溴基)环丙烷的Suzuki–Miyaura 偶联反应。
  • 末端炔烃的溴全氟烷基化。
  • 芳香卤化物和炔烃的无铜Sonogashira 偶联反应,以形成 C-C键。
  • 有机三氟硼酸盐和芳基卤化物的Suzuki 交叉偶联反应。
对于小规模和高通量用途,产品为ChemBeads ChemBeads (928305)

法律信息

cataCXium is a registered trademark of Umicore AG & Co. KG

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

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在文件库中查找您最近购买产品的文档。

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A Modular Approach to the Synthesis of gem-Disubstituted Cyclopropanes.
Harris MR, et al.
Organic Letters, 20(10), 2867-2871 (2018)
The use of carboxylic acids as traceless directing groups for regioselective C-H bond functionalisation.
Font M and Quibell
Chemical Communications (Cambridge, England), 53(41), 5584-5597 (2017)
Construction of 1-Heteroaryl-3-azabicyclo [3.1. 0] hexanes by sp3-sp2 Suzuki-Miyaura and Chan-Evans-Lam Coupling Reactions of Tertiary Trifluoroborates.
Harris MR, et al.
Organic Letters, 19(9), 2450-2453 (2017)
Copper-free Sonogashira cross-coupling reactions: an overview
Mohajer F, et al.
Royal Society of Chemistry Advances, 11, 6885-6925 (2021)
Pd-catalyzed boroperfluoroalkylation of alkynes opens a route to one-pot reductive carboperfluoroalkylation of alkynes with perfluoroalkyl and aryl iodides
Domannski S, et al.
Organic Letters, 13, 5021-5025 (2019)

商品

All of the preformed catalysts used in the kit are air and moisture stable complexes in their commercially available form.

Tools aid in kit setup for organic chemistry techniques, ensuring ease and success.

Materials Included in your KITALYSIS-24PD-2PK High-Throughput Screening Kit

G3 and G4 Buchwald palladium precatalysts are the newest air, moisture, and thermally stable crossing-coupling complexes used in bond formation for their versatility and high reactivity.

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