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Merck
CN

XPC

xeroderma pigmentosum, complementation group C

别名:
RAD4, XP3, XPCC
物种:
UniProtKB ID:
基因ID:
  • Human(7508) Summary: This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
  • Mouse(22591) xeroderma pigmentosum, complementation group C
  • Rat(312560) xeroderma pigmentosum, complementation group C
  • chicken(416039) xeroderma pigmentosum, complementation group C
  • Zebrafish(541386) xeroderma pigmentosum, complementation group C
  • sheep(101109650) xeroderma pigmentosum, complementation group C
  • domestic cat(101080440) xeroderma pigmentosum, complementation group C
  • Horse(100050424) xeroderma pigmentosum, complementation group C
  • dog(476521) xeroderma pigmentosum, complementation group C
  • naked mole-rat(101707002) xeroderma pigmentosum, complementation group C
  • domestic guinea pig(100719007) xeroderma pigmentosum, complementation group C
  • Domestic Rabbit(100346279) xeroderma pigmentosum, complementation group C
  • cow(524274) xeroderma pigmentosum, complementation group C

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Antibodies

货号
说明
物种反应性
应用
Monoclonal Anti-XPC antibody produced in mouse, ,
物种反应性
human, mouse
应用
immunocytochemistry
immunofluorescence

immunohistochemistry

western blot
Anti-XPC (C-terminal) 兔抗, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
immunofluorescence
western blot
Anti-XPC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Anti-XPC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-XPC antibody produced in rabbit, ,
物种反应性
human
应用
immunocytochemistry
immunofluorescence

immunoprecipitation (IP)

western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human XPC,
物种
human
MISSION® esiRNA, targeting mouse Xpc,
物种
mouse