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Merck
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TLR9

toll-like receptor 9

别名:
CD289
物种:
UniProtKB ID:
基因ID:
  • Human(54106) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Jul 2008]
  • Mouse(81897) toll-like receptor 9
  • Rat(338457) toll-like receptor 9
  • naked mole-rat(101715478) toll-like receptor 9
  • cow(282602) toll-like receptor 9
  • Horse(100009693) toll-like receptor 9
  • sheep(494547) toll-like receptor 9
  • dog(403502) toll-like receptor 9
  • Zebrafish(403128) toll-like receptor 9
  • domestic cat(493839) toll-like receptor 9
  • Goat(100860819) toll-like receptor 9

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Antagonist

货号
说明
物种
羟氯喹 硫酸酯, ≥98% (HPLC), powder,
物种
human
硫酸羟氯喹, United States Pharmacopeia (USP) Reference Standard,
物种
human
2-[4-[(7-氯-4-喹啉基)氨基]戊基]氨基乙醇, British Pharmacopoeia (BP) Reference Standard,
物种
human
2-((4-(7-Chloroquinolin-4-ylamino)pentyl)(ethyl)amino)ethanol, ,
物种
human
硫酸羟氯喹, British Pharmacopoeia (BP) Reference Standard,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-TLR9 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse
应用
ELISA
immunofluorescence

immunohistochemistry

western blot
Monoclonal Anti-TLR9 antibody produced in mouse, clone 1E8, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

western blot
ANTI-TLR9 antibody produced in mouse, clone 2H5, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
ANTI-TLR9 antibody produced in mouse, clone 2G3, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Anti-TLR9, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, goat, horse, human, pig, sheep
应用
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human TWF2, RP11-330H6.5,
物种
human
MISSION® esiRNA, targeting human TLR9, RP11-330H6.5,
物种
human