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Merck
CN

H0915

羟氯喹 硫酸酯

≥98% (HPLC), powder, anti-inflammatory

别名:

硫酸羟氯喹, 7-氯-4-[4-(N-乙基-N-b-羟乙基氨基)-1-甲基丁氨基] 喹啉硫酸盐

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关于此项目

经验公式(希尔记法):
C18H26ClN3O · H2SO4
化学文摘社编号:
分子量:
433.95
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
212-019-3
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
Storage condition:
protect from light
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产品名称

羟氯喹 硫酸酯, ≥98% (HPLC), powder

Quality Level

assay

≥98% (HPLC)

form

powder

storage condition

protect from light

color

white to off-white

solubility

H2O: >20 mg/mL

SMILES string

OS(O)(=O)=O.CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12

InChI

1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)

InChI key

JCBIVZZPXRZKTI-UHFFFAOYSA-N

Gene Information

Application

硫酸羟氯喹已:
  • 用作自噬的抑制剂,以处理细胞进行凋亡测定用于研究吡柔比星在膀胱癌细胞系中诱导自噬的作用
  • 用于通过免疫荧光测定来评估羟氯喹对登革病毒-2 (DENV-2)感染的抗病毒机制
  • 用于抑制溶酶体与自噬体的融合

Biochem/physiol Actions

羟氯喹也用于治疗类风湿性关节炎和系统性红斑狼疮。
硫酸羟氯喹是一种抗炎(通过肿瘤坏死因子)、疾病调节抗风湿药物(DMARD)和血红素聚合酶抑制剂。
硫酸羟氯喹是一种抗炎(通过肿瘤坏死因子)、疾病调节抗风湿药物(DMARD)和血红素聚合酶抑制剂。 它可用于治疗疟疾。


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signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

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全球贸易项目编号

货号GTIN
H0915-5MG04061833663592
H0915-25MG04061833663585