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等级
analytical standard
质量水平
方案
≥95.0% (HPLC)
保质期
limited shelf life, expiry date on the label
包装
pkg of 50 mg
技术
HPLC: suitable
gas chromatography (GC): suitable
杂质
≤1.0% water
颜色
white to off-white
应用
forensics and toxicology
pharmaceutical (small molecule)
veterinary
包装形式
neat
储存温度
2-8°C
SMILES字符串
OS(O)(=O)=O.CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12
InChI
1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)
InChI key
JCBIVZZPXRZKTI-UHFFFAOYSA-N
基因信息
human ... TLR7(51284) , TLR9(54106)
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一般描述
硫酸羟氯喹(Hydroxychloroquine Sulphate)是羟氯喹(HCQ,赛能)的盐,它是一种4-氨基喹啉类抗病毒药物。
应用
硫酸羟氯喹可用作分析标准品,用于通过各种分析技术测定药物制剂 和生物样品 中的分析物。
生化/生理作用
硫酸羟氯喹是一种抗炎(通过肿瘤坏死因子)、疾病调节抗风湿药物(DMARD)和血红素聚合酶抑制剂。
硫酸羟氯喹是一种抗炎(通过肿瘤坏死因子)、疾病调节抗风湿药物(DMARD)和血红素聚合酶抑制剂。 它可用于治疗疟疾。
警示用语:
Warning
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Seminars in Arthritis and Rheumatism, 43(2), 264-272 (2013)
High-performance liquid chromatographic assay for hydroxychloroquine and three of its major metabolites, desethylhydroxychloroquine, desethylchloroquine and bidesethylchloroquine, in human plasma
Journal of Chromatography. B, Biomedical Applications, 377(11), 454-459 (1986)
Analysis of blood and urine samples for hydroxychloroquine and three major metabolites by high-performance liquid chromatography with fluorescence detection
Journal of Chromatography. B, Biomedical Applications, 433(11), 197-206 (1988)
Development of a novel ion-pairing HPLC-FL method for the separation and quantification of hydroxychloroquine and its metabolites in whole blood
Biomedical Chromatography, 32(8), e4258-e4258 (2018)
QUALITY BY DESIGN IN THE DEVELOPMENT AND VALIDATION OF ANALYTICAL METHOD BY ULTRAVIOLET-VISIBLE SPECTROPHOTOMETRY FOR QUANTIFICATION OF HYDROXYCHLOROQUINE SULFATE
International Journal of Pharmaceutical Sciences and Research, 5(11), 4666-4666 (2014)
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