所有图片(2)
别名:
AMP-CPP
经验公式（希尔记法）:
C11H18N5O12P3 · xLi+
CAS号:
分子量:
505.21 (free acid basis)
MDL编号:
UNSPSC代码:
41106305
eCl@ss:
32160414
PubChem化学物质编号:
NACRES:
NA.77
推荐产品
质量水平
检测方案
≥93% (HPLC)
形式
solid
颜色
white
溶解性
H2O: 100 mg/mL
储存温度
−20°C
SMILES字符串
[Li+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)CP(O)(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O
InChI
1S/C11H18N5O12P3.Li/c12-9-6-10(14-2-13-9)16(3-15-6)11-8(18)7(17)5(27-11)1-26-29(19,20)4-30(21,22)28-31(23,24)25;/h2-3,5,7-8,11,17-18H,1,4H2,(H,19,20)(H,21,22)(H2,12,13,14)(H2,23,24,25);/q;+1/p-1/t5-,7-,8-,11-;/m1./s1
InChI key
NVHVREPTGDOYIC-YCSZXMBFSA-M
基因信息
human ... P2RX1(5023)
相关类别
应用
α,β-亚甲基腺苷 5'-三磷酸锂盐已：
- 用作P2-嘌呤受体激动剂 (P2X)，以分析其对尾核星形胶质细胞膜电导的影响；
- 用作P2X受体激动剂， 增加卫星细胞神经元中的钙电流，以
- 确定嘌呤能激动剂对大鼠P2Y受体的功能敏感性，并确定其对发展外窦细胞的影响
生化/生理作用
P2 嘌呤受体激动剂，在 P2X 亚型比 ATP 更有效。
特点和优势
该化合物的相关信息整理于受体分类和信号转导手册的 P2受体：P2X 离子通道家族和P2 受体：《受体分类和信号转导》手册的 P2Y G 蛋白家族页面有该化合物的介绍。想要浏览手册的其他页面， 请单击此处。
外形
吸湿性固体
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Tanumoy Mondol et al.
Nucleic acids research, 47(4), 1977-1986 (2019-01-04)
DNA polymerase delta (Pol δ) is responsible for the elongation and maturation of Okazaki fragments in eukaryotic cells. Proliferating cell nuclear antigen (PCNA) recruits Pol δ to the DNA and serves as a processivity factor. Here, we show that PCNA
Catherine A Regni et al.
The EMBO journal, 28(13), 1953-1964 (2009-06-06)
The 39-kDa Escherichia coli enzyme MccB catalyses a remarkable posttranslational modification of the MccA heptapeptide during the biosynthesis of microcin C7 (MccC7), a 'Trojan horse' antibiotic. The approximately 260-residue C-terminal region of MccB is homologous to ubiquitin-like protein (UBL) activating
G Burnstock et al.
General pharmacology, 16(5), 433-440 (1985-01-01)
It is suggested that the P2-purinoceptor may be separated into two subtypes largely on the basis of the rank order of agonist potency of structural analogues of ATP and also on the activity of antagonists at the P2-purinoceptor: Subtype 1
D J Trezise et al.
British journal of pharmacology, 112(1), 282-288 (1994-05-01)
1. We have previously found that the P2x-purinoceptor agonist, alpha, beta-methylene adenosine 5'-triphosphate (alpha, beta-methylene ATP), depolarizes the rat cervical vagus nerve, measured with a 'grease-gap' extracellular recording technique. This effect was attenuated by the P2 purinoceptor antagonist, suramin. In
GABA-mediated modulation of ATP-induced intracellular calcium responses in nodose ganglion neurons of the rat
Yokoyama T, et al.
Neuroscience Letters, 584, 168-172 (2015)
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