IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
别名:
IMPD2, IMPDH-II
物种:
Human IMPDH2 (3615), Mouse Impdh2 (23918), Rat Impdh2 (301005), dog IMPDH2 (476630), Zebrafish impdh2 (317745), domestic guinea pig Impdh2 (100730768), naked mole-rat Impdh2 (101701391), domestic cat IMPDH2 (101080693), cow IMPDH2 (511969), sheep IMPDH2 (101107823) ...展开
UniProtKB ID:
基因ID:
- Human(3615) Summary: This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. [provided by RefSeq, Jul 2008]
- Mouse(23918) inosine 5'-phosphate dehydrogenase 2
- Rat(301005) IMP (inosine 5'-monophosphate) dehydrogenase 2
- dog(476630) IMP (inosine 5'-monophosphate) dehydrogenase 2
- Zebrafish(317745) IMP (inosine monophosphate) dehydrogenase 2
- domestic guinea pig(100730768) IMP (inosine 5'-monophosphate) dehydrogenase 2
- naked mole-rat(101701391) IMP (inosine 5'-monophosphate) dehydrogenase 2
- domestic cat(101080693) IMP (inosine 5'-monophosphate) dehydrogenase 2
- cow(511969) IMP (inosine 5'-monophosphate) dehydrogenase 2
- sheep(101107823) IMP (inosine 5'-monophosphate) dehydrogenase 2
- Domestic Rabbit(100355621) IMP (inosine 5'-monophosphate) dehydrogenase 2
- chicken(416058) IMP (inosine 5'-monophosphate) dehydrogenase 2
- Horse(100063255) IMP (inosine 5'-monophosphate) dehydrogenase 2
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Antibodies
产品编号
说明
物种反应性
应用
Anti IMPDH2 Antibody, clone 23GB6670, Rabbit Monoclonal, clone 23GB6670, recombinant rabbit monoclonal, expressed in HEK293 cells,
物种反应性
human, rat
应用
flow cytometry
western blot
western blot
Anti-IMPDH2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-IMPDH2 antibody produced in mouse, clone 1E12-B6, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-IMPDH2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
应用
western blot
Small Molecule - Inhibitor
Proteins
产品编号
说明
物种