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Merck
CN

CYP19A1

cytochrome P450, family 19, subfamily A, polypeptide 1

别名:
ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM
物种:
UniProtKB ID:
基因ID:
  • Human(1588) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. [provided by RefSeq, Jul 2008]
  • Mouse(13075) cytochrome P450, family 19, subfamily a, polypeptide 1
  • Rat(25147) cytochrome P450, family 19, subfamily a, polypeptide 1
  • Goat(100861413) cytochrome P450, family 19, subfamily A, polypeptide 1
  • Horse(100009712) cytochrome P450, family 19, subfamily A, polypeptide 1
  • dog(494003) cytochrome P450, family 17, subfamily A, polypeptide 1
  • chicken(414854) cytochrome P450, family 19, subfamily A, polypeptide 1
  • Domestic Rabbit(100328545) cytochrome P450, family 19, subfamily A, polypeptide 1
  • cow(281740) cytochrome P450, family 19, subfamily A, polypeptide 1

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Antibodies

货号
说明
物种反应性
应用
Anti-Aromatase Antibody, clone 1D23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, monkey
应用
affinity binding assay
immunohistochemistry

western blot
Anti-Cytochrome P450 19A1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

immunohistochemistry

western blot
抗-CYP19A1 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-Aromatase Antibody, from rabbit, purified by affinity chromatography,
物种反应性
bovine, canine, chimpanzee, human, pig, porcine, rhesus macaque
应用
western blot
Anti-Aromatase (CYP19A1) Antibody, clone 5C5N7, Rabbit Monoclonal, ,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot

Cell Lines

货号
说明
物种
CypExpress 芳香酶, ,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
来曲唑, ≥98% (HPLC),
物种
human
来曲唑, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
来曲唑, British Pharmacopoeia (BP) Reference Standard,
物种
human
(R)-(+)-氨鲁米特, 97%,
物种
human
鹰嘴豆芽素A, ,
物种
human, mouse

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Cyp19a1,
物种
mouse
MISSION® esiRNA, targeting human CYP19A1,
物种
human