跳转至内容

Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

Merck
CN
所有图片(1)

主要文件

查看所有文档

安全信息

PZ0006

Sigma-Aldrich

依西美坦

≥98% (HPLC)

别名:

6-Methyleneandrosta-1,4-diene-3,17-dione

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C20H24O2
CAS号:
107868-30-4
分子量:
296.40
MDL编号:
MFCD00866994
UNSPSC代码:
51111800
PubChem化学物质编号:
329823675
NACRES:
NA.77
产品PZ0006监管中，请联系销售询价或购买 联系客户支持

质量水平

100

方案

≥98% (HPLC)

表单

powder

旋光性

[α]/D +250 to +300°, c = 1 in methanol

颜色

white to off-white

溶解性

DMSO: ≥20 mg/mL

储存温度

2-8°C

SMILES字符串

C[C@]12CC[C@H]3[C@@H](CC(=C)C4=CC(=O)C=C[C@]34C)[C@@H]1CCC2=O

InChI

1S/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1

InChI key

BFYIZQONLCFLEV-DAELLWKTSA-N

正在寻找类似产品? 访问 产品对比指南

比较类似商品

查看完整比较结果

显示差异

1 of 4

此商品
G5168PZ0111M4074
Exemestane ≥98% (HPLC)

PZ0006

Exemestane

(Z)-Guggulsterone ≥89% (HPLC), powder

G5168

(Z)-Guggulsterone

PD-407824 ≥98% (HPLC)

PZ0111

PD-407824

Mometasone furoate ≥98% (HPLC)

M4074

Mometasone furoate

form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥89% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: ≥20 mg/mL

solubility

DMSO: 5 mg/mL

solubility

DMSO: >10 mg/mL

solubility

DMSO: ≥20 mg/mL

color

white to off-white

color

light yellow

color

yellow to orange

color

white to off-white

生化/生理作用

Exemestane is a steroidal antiestrogen and irreversible aromatase inhibitor. Exemestane acts as a false substrate for the aromatase enzyme. Exemestane also prevents the conversion of androgens to estrogens and is used to treat estrogen-dependent breast cancer.
Exemestane is a steroidal antiestrogen; aromatase inhibitor.

特点和优势

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

象形图

Health hazardEnvironment
GHS08,GHS09

警示用语：

Danger

危险声明

H360,H411

危险分类

Aquatic Chronic 2 - Repr. 1B

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    0000362182
    0000362182
    037M4720V
    100M4705

    没有发现合适的版本？

    如果您需要特殊版本，可通过批号或批次号查找具体证书。

    搜索COA

    已有该产品？

    在文件库中查找您最近购买产品的文档。

    访问文档库

    Willemien van de Water et al.
    European journal of cancer (Oxford, England : 1990), 49(2), 297-304 (2012-09-08)
    Multiple studies suggest better efficacy of chemotherapy in invasive ductal breast carcinomas (IDC) than invasive lobular breast carcinomas (ILC). However, data on efficacy of adjuvant endocrine therapy regimens and histological subtypes are sparse. This study assessed endocrine therapy efficacy in
    Willemien van de Water et al.
    The oncologist, 18(1), 8-13 (2012-12-25)
    For postmenopausal patients with hormone-sensitive breast cancer, outcome is worse with increasing age at diagnosis. The aim of this study was to assess the incidence of breast cancer recurrence (locoregional and distant), and contralateral breast cancer by age at diagnosis.
    Nan Soon Wong et al.
    Expert opinion on pharmacotherapy, 6(13), 2353-2363 (2005-10-13)
    Breast cancer is a major health problem in developed countries. Endocrine therapy is a key component in the management of hormone receptor-positive disease. Although tamoxifen has historically been the gold standard in the first-line management of early and advanced breast
    John M S Bartlett et al.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 30(36), 4477-4484 (2012-10-10)
    Some postmenopausal patients with hormone-sensitive early breast cancer remain at high risk of relapse despite endocrine therapy and, in addition, might benefit from adjuvant chemotherapy. The challenge is to prospectively identify such patients. The Mammostrat test uses five immunohistochemical markers
    John Fr Robertson et al.
    The Lancet. Oncology, 14(3), 228-235 (2013-02-19)
    Insulin-like growth factors (IGF-1 and IGF-2) bind to the IGF-1 receptor (IGF-1R), increasing cell proliferation and survival. Ganitumab is a monoclonal IgG1 antibody that blocks IGF-1R. We tested the efficacy and safety of adding ganitumab to endocrine treatment for patients
    查看所有相关文献

    我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

    联系客户支持