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Nanomaterials for Biomedical Applications

Dendrimers are a class of nano-sized materials that are used to develop life-saving technologies. Single-wall carbon nanotubes are used to make miniaturized sensors for DNA, pathogens, and chemicals – for example glucose sensors. Multi-wall nanotubes, nanoclays, and ceramic nanoparticles are incorporated in ultra-strong polymer nanocomposites that will be used in orthopedic, for example joint-replacement, applications. Nanoparticles can also be used to make nano-textured substrates to support attachment and growth of cells for tissue engineering. Hydroxyapatite nanopowders (Product No. 677418), incorporated in biodegradable polymer composites¹ or deposited on biocompatible substrates², have been shown to promote adhesion and proliferation of bone-forming (osteoblast) cells. We are looking forward to offering new nanomaterials tools to accelerate research in biotechnology and medicine.

Figure 1: Hydroxyapatite Nanopowder

Molecular Formula [Ca₅(OH)(PO₄)₃]_x
Average Particle Size 150 – 200 nm
Surface Area > 9.4 m²/g
Available in 5 g pack size

Materials

Product Number	Product Name	Product Description
677418	Hydroxyapatite	nanopowder, <200 nm particle size (BET), ≥97%, synthetic
702153	Hydroxyapatite	nanoparticles, dispersion, 10 wt. % in H₂O, <200 nm particle size (BET)
693863	Hydroxyapatite	nanopowder, <200 nm particle size (BET), contains 5 wt. % silica as dopant, synthetic

References

1.

Kim S, Sun Park M, Jeon O, Yong Choi C, Kim B. 2006. Poly(lactide-co-glycolide)/hydroxyapatite composite scaffolds for bone tissue engineering. Biomaterials. 27(8):1399-1409. https://doi.org/10.1016/j.biomaterials.2005.08.016

2.

Sato M, Sambito MA, Aslani A, Kalkhoran NM, Slamovich EB, Webster TJ. 2006. Increased osteoblast functions on undoped and yttrium-doped nanocrystalline hydroxyapatite coatings on titanium. Biomaterials. 27(11):2358-2369. https://doi.org/10.1016/j.biomaterials.2005.10.041