- GPR62 constitutively activates cAMP signaling but is dispensable for male fertility in mice.
GPR62 constitutively activates cAMP signaling but is dispensable for male fertility in mice.
Reproduction (Cambridge, England) (2017-09-16)
Tomoyuki Muroi, Yuri Matsushima, Ryota Kanamori, Hikari Inoue, Wataru Fujii, Keiichiro Yogo
PMID28912303
ABSTRACT
G-protein-coupled receptors (GPCRs) participate in diverse physiological functions and are promising targets for drug discovery. However, there are still over 140 orphan GPCRs whose functions remain to be elucidated.
MATERIALS
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Brand
Product Description
Sigma-Aldrich
Dulbecco′s Modified Eagle′s Medium - high glucose, With 4500 mg/L glucose, L-glutamine, and sodium bicarbonate, without sodium pyruvate, liquid, sterile-filtered, suitable for cell culture
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Sigma-Aldrich
Antibiotic Antimycotic Solution (100×), Stabilized, with 10,000 units penicillin, 10 mg streptomycin and 25 μg amphotericin B per mL, 0.1 μm filtered, BioReagent, suitable for cell culture
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