All Photos(1)

Documents

A5955

Antibiotic Antimycotic Solution (100×), Stabilized

Name: Antibiotic Antimycotic Solution (100×), Stabilized
Brand: SIGMA

suspension, suitable for cell culture, BioReagent

Synonym(s):

Penicillin-Streptomycin-Amphotericin B Suspension

Sign Into View Organizational & Contract Pricing

All Photos(1)

About This Item

MDL number:

MFCD00130520

UNSPSC Code:

12352207

NACRES:

NA.76

product name

Antibiotic Antimycotic Solution (100×), Stabilized, with 10,000 units penicillin, 10 mg streptomycin and 25 μg amphotericin B per mL, 0.1 μm filtered, BioReagent, suitable for cell culture

Quality Level

200

sterility

0.1 μm filtered

product line

BioReagent

form

suspension

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

yellow

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria
fungi
yeast

application(s)

agriculture

Mode of action

cell wall synthesis | interferes

shipped in

dry ice

storage temp.

−20°C

Looking for similar products? Visit Product Comparison Guide

Related Categories

Antibiotics

General description

Antibiotic Antimycotic Solution is formulated to contain 10,000 units penicillin, 10 mg streptomycin and 25μg Amphotericin B per mL, and is solubilized in a proprietary citrate buffer. It is recommended for use in cell culture applications at 10mL/L. Antibioticantimycotic solution is generally used to prevent the growth of harmful microorganisms including bacteria and fungi in cell culture media.

Application

Antibiotic antimycotic solution has been used:

as a supplement in different types of cell culture media.
as a component of phosphate buffer saline (PBS) sterile solution to prevent contamination of periodontal ligament fibroblasts (PDLF) tissues that are isolated and cultured in the experiments.
as a component of storage solution for preserving tracheal segments harvested for subsequent experimental investigation.

Biochem/physiol Actions

Mode of Action: Penicillin acts by inhibiting bacterial cell-wall synthesis. Streptomycin inhibits prokaryote protein synthesis by preventing the transition from initiation complex to chain-elongating ribosome and causes miscoding. Amphotericin B interferes with fungal membrane permeability by forming channels in the membranes and causing small molecules to leak out.

Antimicrobial spectrum: Includes Gram-negative bacteria, Gram-positive bacteria, fungi and yeasts.

also commonly purchased with this product

Product No.

Description

Pricing

890890P

18:1 TAP (DOTAP), Avanti Research^™ - A Croda Brand

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H317

Precautionary Statements

P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364

Hazard Classifications

Skin Sens. 1

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Effect of biocide addition on plantlet growth and contamination occurrence during the in vitro culture of blueberry

Sun YH, et al.

Journal of plant biotechnology, 42(2) (2015)

Mechanisms of activation of eNOS by 20-HETE and VEGF in bovine pulmonary artery endothelial cells.

Yuenmu Chen et al.

American journal of physiology. Lung cellular and molecular physiology, 291(3), L378-L385 (2006-05-09)

We have demonstrated that VEGF-induced dilation of bovine pulmonary arteries is associated with activation of cytochrome P-450 family 4 (CYP4) enzymes and eNOS. We hypothesized that VEGF and the CYP4 product 20-HETE would trigger common downstream pathways of intracellular signaling

Probing spermiogenesis: a digital strategy for mouse acrosome classification.

Alessandro Taloni et al.

Scientific reports, 7(1), 3748-3748 (2017-06-18)

Classification of morphological features in biological samples is usually performed by a trained eye but the increasing amount of available digital images calls for semi-automatic classification techniques. Here we explore this possibility in the context of acrosome morphological analysis during

Poly (3-hydroxybutyrate-co-3-hydroxyvalerate)/fibrinogen/bredigite nanofibrous membranes and their integration with osteoblasts for guided bone regeneration.

Monireh Kouhi et al.

Journal of biomedical materials research. Part A, 107(6), 1154-1165 (2019-01-13)

Guided bone regeneration (GBR) has been established to be an effective method for the repair of defective tissues, which is based on isolating bone defects with a barrier membrane for faster tissue reconstruction. The aim of the present study is

Calcium phosphate-induced renal epithelial injury and stone formation: involvement of reactive oxygen species.

Kinue Aihara et al.

Kidney international, 64(4), 1283-1291 (2003-09-13)

Crystal formation and retention are critical events for the formation of kidney stones. Oxalate and calcium oxalate (CaOx) crystals are injurious to renal epithelium, and membranes of injured cells promote crystal adherence and retention. Calcium phosphate (CaP) is the most

View All Related Papers

Articles

Antifungals Reagents in Cell Culture

Prevent fungal, yeast, and mold contamination in cell cultures. Discover the best antifungal agent for your cultures with the extensive Sigma® antifungal collection.