Skip to Content

很抱歉,目前系统维护中。在此期间,网站下单功能无法使用。给您带来不便,深表歉意。如需其他帮助,请联系客户联络中心:400 620 3333。

Merck
CN
  • Artificial receptors for the extraction of nucleoside metabolite 7-methylguanosine from aqueous media made by molecular imprinting.

Artificial receptors for the extraction of nucleoside metabolite 7-methylguanosine from aqueous media made by molecular imprinting.

Journal of chromatography. A (2014-09-15)
Aleksandra Krstulja, Coralie De Schutter, Patrick Favetta, Panagiotis Manesiotis, Luigi A Agrofoglio
ABSTRACT

A series of imprinted polymers targeting nucleoside metabolites, prepared using a template analogue approach, are presented. These were prepared following selection of the optimum functional monomer by solution association studies using (1)H NMR titrations whereby methacrylic acid was shown to be the strongest receptor with and affinity constant of 621±51Lmol(-1)vs. 110±16Lmol(-1) for acrylamide. The best performing polymers were prepared using methanol as porogenic co-solvent and although average binding site affinities were marginally reduced, 2.3×10(4)Lmol(-1)vs. 2.7×10(4)Lmol(-1) measured for a polymer prepared in acetonitrile, these polymers contained the highest number of binding sites, 5.27μmolg(-1)vs. 1.64μmolg(-1), while they also exhibited enhanced selectivity for methylated guanosine derivatives. When applied as sorbents in the extraction of nucleoside derivative cancer biomarkers from synthetic urine samples, significant sample clean-up and recoveries of up to 90% for 7-methylguanosine were achieved.

MATERIALS
Product Number
Brand
Product Description

Supelco
Water, for TOC analysis
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 L
Please contact Customer Service for Availability
CN¥539.02
Sigma-Aldrich
Methanol, NMR reference standard
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 pkg
Please contact Customer Service for Availability
CN¥1,604.46
1 pkg
Please contact Customer Service for Availability
CN¥2,521.35
Sigma-Aldrich
Acrylamide, ≥98.0%
Pricing and availability is not currently available.
Sigma-Aldrich
Acrylamide, ≥99.9%
Pricing and availability is not currently available.
Supelco
Water, suitable for ion chromatography
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
2.5 L
Please contact Customer Service for Availability
CN¥732.52
5 L
Estimated to ship on April 07, 2025
Details...
CN¥1,207.45
Supelco
Acrylamide, analytical standard
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
100 mg
Please contact Customer Service for Availability
CN¥630.35
Sigma-Aldrich
Acrylic acid, anhydrous, contains 200 ppm MEHQ as inhibitor, 99%
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
5 g
Estimated to ship on April 07, 2025
Details...
CN¥586.92
1 L
Please contact Customer Service for Availability
CN¥670.94
100 g
Estimated to ship on April 07, 2025
Details...
CN¥715.67
500 g
Estimated to ship on April 07, 2025
Details...
CN¥833.40
3 kg
Please contact Customer Service for Availability
CN¥1,510.06
2.5 L
Please contact Customer Service for Availability
CN¥1,560.53
18 kg
Please contact Customer Service for Availability
CN¥6,420.61
Supelco
Density Standard 998 kg/m3, H&D Fitzgerald Ltd. Quality
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
10 mL
Please contact Customer Service for Availability
CN¥2,398.54
Sigma-Aldrich
Methanol, purification grade, 99.8%
Pricing and availability is not currently available.
Sigma-Aldrich
Methanol, anhydrous, 99.8%
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
100 mL
Estimated to ship on April 07, 2025
Details...
CN¥571.58
1 L
Estimated to ship on April 07, 2025
Details...
CN¥804.93
2 L
Estimated to ship on April 07, 2025
Details...
CN¥1,270.48
18 L
Please contact Customer Service for Availability
CN¥8,299.78
Sigma-Aldrich
Acrylamide, for Northern and Southern blotting, powder blend
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
100 g
Please contact Customer Service for Availability
CN¥1,012.11
500 g
Please contact Customer Service for Availability
CN¥3,508.65
1 kg
Please contact Customer Service for Availability
CN¥5,589.09
Sigma-Aldrich
Water, for molecular biology, sterile filtered
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
100 mL
Estimated to ship on April 07, 2025
Details...
CN¥868.10
500 mL
Please contact Customer Service for Availability
New, lower price on this item!
CN¥1,043.30
1 L
Please contact Customer Service for Availability
CN¥1,866.31
6 x 100 mL
Estimated to ship on April 07, 2025
Details...
CN¥3,800.16
Sigma-Aldrich
Cytidine, 99%
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on April 07, 2025
Details...
CN¥227.11
10 g
Estimated to ship on April 07, 2025
Details...
CN¥657.85
Supelco
Methanol, analytical standard
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
5 mL
Estimated to ship on April 07, 2025
Details...
CN¥559.29
10 mL
Estimated to ship on April 07, 2025
Details...
CN¥1,348.63
Sigma-Aldrich
Sodium acrylate, 97%
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
25 g
Estimated to ship on April 07, 2025
Details...
CN¥807.13
100 g
Estimated to ship on April 07, 2025
Details...
CN¥2,369.59
Sigma-Aldrich
Water, Nuclease-Free Water, for Molecular Biology
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 L
Estimated to ship on April 07, 2025
Details...
CN¥1,218.86
10 x 50 mL
Estimated to ship on April 07, 2025
Details...
CN¥1,612.69
6 x 1 L
Estimated to ship on April 07, 2025
Details...
CN¥3,546.81
10 L
Estimated to ship on April 07, 2025
Details...
CN¥5,124.10
Sigma-Aldrich
E-Toxate Water, endotoxin, free
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
10 mL
Please contact Customer Service for Availability
CN¥589.97
30 mL
Please contact Customer Service for Availability
CN¥838.39
Sigma-Aldrich
Acrylamide, suitable for electrophoresis, ≥99% (HPLC), powder
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
100 g
Estimated to ship on April 07, 2025
Details...
CN¥1,161.71
500 g
Estimated to ship on April 07, 2025
Details...
CN¥3,478.13
1 kg
Estimated to ship on April 07, 2025
Details...
CN¥5,879.07
Sigma-Aldrich
Acrylamide, suitable for electrophoresis, ≥99%
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
100 g
Estimated to ship on April 07, 2025
Details...
CN¥795.01
500 g
Estimated to ship on April 07, 2025
Details...
CN¥1,423.10
CN¥1,067.33
6 x 100 g
Please contact Customer Service for Availability
CN¥1,828.32
1 kg
Estimated to ship on April 07, 2025
Details...
CN¥2,211.25
6 x 500 g
Please contact Customer Service for Availability
CN¥3,732.40
2.5 kg
Estimated to ship on April 07, 2025
Details...
CN¥4,195.22
CN¥3,146.42
Sigma-Aldrich
Acrylamide, for molecular biology, ≥99% (HPLC)
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
25 g
Estimated to ship on April 07, 2025
Details...
CN¥419.13
100 g
Estimated to ship on April 07, 2025
Details...
CN¥1,235.04
6 x 100 g
Please contact Customer Service for Availability
CN¥2,976.37
500 g
Estimated to ship on April 07, 2025
Details...
CN¥3,666.71
CN¥3,116.71
1 kg
Please contact Customer Service for Availability
CN¥5,481.45
2.5 kg
Please contact Customer Service for Availability
CN¥12,274.91
Sigma-Aldrich
Water, PCR Reagent
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 vial
Estimated to ship on April 07, 2025
Details...
New, lower price on this item!
CN¥350.87
CN¥105.26
5 vials
Please contact Customer Service for Availability
New, lower price on this item!
CN¥1,215.24
Sigma-Aldrich
Cytidine, BioReagent, suitable for cell culture, powder, ≥99%
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 g
Estimated to ship on April 07, 2025
Details...
CN¥357.20
5 g
Estimated to ship on April 07, 2025
Details...
CN¥645.04
CN¥516.03
50 g
Estimated to ship on April 07, 2025
Details...
CN¥2,451.85
Supelco
Methanol, Pharmaceutical Secondary Standard; Certified Reference Material
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
3 x 1.5 mL
Estimated to ship on April 07, 2025
Details...
CN¥1,437.99
Supelco
Residual Solvent - Acetonitrile(solution in DMSO), Pharmaceutical Secondary Standard; Certified Reference Material
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
3 x 1.2 mL
Estimated to ship on April 07, 2025
Details...
CN¥1,437.99
Sigma-Aldrich
Water, for cell biology, sterile ultrafiltered
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
100 mL
Estimated to ship on April 07, 2025
Details...
CN¥320.21
CN¥272.17
500 mL
Please contact Customer Service for Availability
CN¥730.59
1 L
Please contact Customer Service for Availability
New, lower price on this item!
CN¥1,276.21
Sigma-Aldrich
Acrylamide, purum, ≥98.0% (GC)
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
250 g
Please contact Customer Service for Availability
CN¥697.40
1 kg
Estimated to ship on April 07, 2025
Details...
CN¥1,455.12
5 kg
Please contact Customer Service for Availability
CN¥5,831.04
Supelco
Acrylamide, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
100 mg
Please contact Customer Service for Availability
CN¥1,527.35
Sigma-Aldrich
Methanol, ACS reagent, ≥99.8%
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
1 L
Please contact Customer Service for Availability
CN¥771.67
4 x 4 L
Please contact Customer Service for Availability
CN¥7,386.96
Sigma-Aldrich
Methanol, Laboratory Reagent, ≥99.6%
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
2.5 L
Estimated to ship on April 07, 2025
Details...
CN¥487.82
1 L
Estimated to ship on April 07, 2025
Details...
CN¥522.26
18 L
Please contact Customer Service for Availability
CN¥2,837.44
4 x 4 L
Please contact Customer Service for Availability
CN¥3,529.97
160 kg
Please contact Customer Service for Availability
CN¥29,378.69
Sigma-Aldrich
Methanol, ACS spectrophotometric grade, ≥99.9%
Sign Into View Organizational & Contract Pricing
SKUPack SizeAvailabilityPriceQuantity
500 mL
Estimated to ship on April 07, 2025
Details...
CN¥661.73
1 L
Estimated to ship on April 07, 2025
Details...
CN¥1,021.00
2 L
Please contact Customer Service for Availability
CN¥1,406.40
16 L
Please contact Customer Service for Availability
CN¥3,419.92
4 x 2 L
Please contact Customer Service for Availability
CN¥4,705.08