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1356632

USP

Ketoprofen

Name: Ketoprofen
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

2-(3-Benzoylphenyl)propionic acid

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About This Item

Empirical Formula (Hill Notation):

C₁₆H₁₄O₃

CAS Number:

22071-15-4

Molecular Weight:

254.28

MDL number:

MFCD00055790

UNSPSC Code:

41116107

PubChem Substance ID:

329750217

NACRES:

NA.24

grade

pharmaceutical primary standard

API family

ketoprofen

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CC(C(O)=O)c1cccc(c1)C(=O)c2ccccc2

InChI

1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)

InChI key

DKYWVDODHFEZIM-UHFFFAOYSA-N

Gene Information

human ... PTGS1(5742) , PTGS2(5743)

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Related Categories

Analytical Reference Standards

Pharmacopeia & Metrological Institute Standards

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Ketoprofen USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Ketoprofen Capsules
Ketoprofen Extended-Release Capsules

Biochem/physiol Actions

Non-steroidal anti-inflammatory compound that is selective for COX-1.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

related product

Product No.

Description

Pricing

1356643

1356563

1356552

BP668

Ketoprofen, British Pharmacopoeia (BP) Reference Standard

BP667

Ketoprofen ethyl ester, British Pharmacopoeia (BP) Reference Standard

PHR2877

PHR2955

PHR3018

Pictograms

GHS06,GHS09

Signal Word

Danger

Hazard Statements

H301,H315,H319,H400

Precautionary Statements

P264 - P273 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Single dose oral ketoprofen and dexketoprofen for acute postoperative pain in adults.

Jodie Barden et al.

The Cochrane database of systematic reviews, (4)(4), CD007355-CD007355 (2009-10-13)

Ketoprofen is a non-selective non-steroidal anti-inflammatory drug (NSAID) used to treat acute and chronic painful conditions. Dexketoprofen is the (S)-enantiomer, which is believed to confer analgesia. Theoretically dexketoprofen is expected to provide equivalent analgesia to ketoprofen at half the dose

Clinical pharmacokinetics of ketoprofen and its enantiomers.

F Jamali et al.

Clinical pharmacokinetics, 19(3), 197-217 (1990-09-01)

Ketoprofen, a potent nonsteroidal anti-inflammatory drug (NSAID) of the 2-arylpropionic acid class, has been used clinically for over 15 years in Europe, and has recently been introduced in the United States. Although it possesses a chiral centre, with only the

Mucoadhesive beads of gellan gum/pectin intended to controlled delivery of drugs.

Fabíola Garavello Prezotti et al.

Carbohydrate polymers, 113, 286-295 (2014-09-27)

Gellan gum/pectin beads were prepared by ionotropic gelation, using Al(3+) as crosslinker. High yield (92.76%) and entrapment efficiency (52.22-88.78%) were reached. Beads exhibited high circularity (0.730-0.849) and size between 728.95 and 924.56 μm. Particle size and circularity was increased by

Photosensitivity to ketoprofen: mechanisms and pharmacoepidemiological data.

H Bagheri et al.

Drug safety, 22(5), 339-349 (2000-06-01)

The topical use of nonsteroidal anti-inflammatory drugs (NSAIDs), widely used for moderate acute and chronic painful conditions, is one of several strategies used to improve the tolerability profile of NSAIDs, particularly with regard to gastric and renal adverse effects. However

Photosensitivity induced by fibric acid derivatives and its relation to photocontact dermatitis to ketoprofen.

G Serrano et al.

Journal of the American Academy of Dermatology, 27(2 Pt 1), 204-208 (1992-08-01)

Photosensitivity reactions to fibric acid derivatives are not well understood and have been rarely reported. The aim of this study was to describe two cases of photosensitivity, one induced by fenofibrate and one by bezafibrate; to study the in vivo

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