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Merck
CN

1193301

USP

Diethylene glycol monoethyl ether

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

2-(2-Ethoxyethoxy)ethanol, CARBITOL™, Diethylene glycol ethyl ether, Ethyldiglycol

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About This Item

Linear Formula:
C2H5OCH2CH2OCH2CH2OH
CAS Number:
111-90-0
Molecular Weight:
134.17
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329749579
MDL number:
MFCD00002872
Beilstein/REAXYS Number:
1736441

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Product Name

Diethylene glycol monoethyl ether, United States Pharmacopeia (USP) Reference Standard

InChI

1S/C6H14O3/c1-2-8-5-6-9-4-3-7/h7H,2-6H2,1H3

SMILES string

CCOCCOCCO

InChI key

XXJWXESWEXIICW-UHFFFAOYSA-N

grade

pharmaceutical primary standard

vapor density

4.63 (vs air)

vapor pressure

0.12 mmHg ( 20 °C)

API family

diethylene glycol

expl. lim.

1.2 %, 135 °F
23.5 %, 182 °F

manufacturer/tradename

USP

refractive index

n20/D 1.427 (lit.)

bp

202 °C (lit.)

density

0.999 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

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Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Application

Diethylene glycol monoethyl ether USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Legal Information

CARBITOL is a trademark of The Dow Chemical Company or an affiliated company of Dow

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

204.8 °F - closed cup

flash_point_c

96 °C - closed cup

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David W Osborne
Journal of cosmetic dermatology, 10(4), 324-329 (2011-12-14)
The solvent diethylene glycol monoethyl ether (DEGEE) is currently used in over 500 cosmetic products and has enabled the formulation of a topical 5% dapsone gel for the treatment of acne. It is anticipated that this common cosmetic ingredient will
J E Riviere et al.
Journal of veterinary pharmacology and therapeutics, 37(5), 435-444 (2014-03-22)
Topical application of ectoparasiticides for flea and tick control is a major focus for product development in animal health. The objective of this work was to develop a quantitative structure permeability relationship (QSPeR) model sensitive to formulation effects for predicting
Suresh Kumar et al.
Journal of cellular biochemistry, 116(6), 985-997 (2015-01-07)
In this study, we for the first time explored the cellular and molecular mechanism of anticancer properties of fascaplysin, a marine sponge-derived alkaloid. Our study demonstrated that fascaplysin induced a cooperative interaction between apoptotic and autophagic pathways to induce cytotoxicity
Changkyu Kim et al.
Nanoscale, 7(15), 6627-6635 (2015-03-21)
The realization of air-stable nanoparticles, well-formulated nanoinks, and conductive patterns based on copper is a great challenge in low-cost and large-area flexible printed electronics. This work reports the synthesis of a conductively interconnected copper structure via thermal sintering of copper
Petra O Nnamani et al.
International journal of pharmaceutics, 477(1-2), 208-217 (2014-10-08)
NLC topical formulation as an alternative to oral and parenteral (IM) delivery of artemether (ART), a poorly water-soluble drug was designed. A Phospholipon 85G-modified Gelucire 43/01 based NLC formulation containing 75% Transcutol was chosen from DSC studies and loaded with
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