Skip to Content
Merck
CN

BP1101

2-[4-[(7-Chloro-4-quinolinyl)amino]pentyl] amino ethanol

British Pharmacopoeia (BP) Reference Standard

Synonym(s):

Hydroxychloroquine sulfate, 7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinoline sulfate

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C18H26ClN3O · H2SO4
CAS Number:
747-36-4
Molecular Weight:
433.95
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
MFCD00078203

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

2-[4-[(7-Chloro-4-quinolinyl)amino]pentyl] amino ethanol, British Pharmacopoeia (BP) Reference Standard

InChI

1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)

SMILES string

OS(O)(=O)=O.CCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12

InChI key

JCBIVZZPXRZKTI-UHFFFAOYSA-N

grade

pharmaceutical primary standard

agency

BP

API family

hydroxychloroquine

form

solid

shelf life

limited shelf life, expiry date on the label

packaging

pkg of 25 mg

manufacturer/tradename

BP

storage condition

OK to freeze

color

off-white

mp

238-241 °C

solubility

water: soluble

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

shipped in

ambient

storage temp.

2-8°C

Gene Information

human ... TLR7(51284), TLR9(54106)

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

2-[4-[(7-Chloro-4-quinolinyl)amino]pentyl] amino ethanol BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Biochem/physiol Actions

Hydroxychloroquine sulfate is an anti-inflammatory (via TNF), disease-modifying antirheumatic drug (DMARD), and a heme polymerase inhibitor.
Hydroxychloroquine sulfate is an anti-inflammatory (via TNF), disease-modifying antirheumatic drug (DMARD), and a heme polymerase inhibitor. It is used in treating malaria.

General description

2-[4-[(7-Chloro-4-quinolinyl)amino]pentyl] amino ethanol (Hydroxychloroquine Sulfate) is a salt of hydroxychloroquine (HCQ, Plaquenil), a 4-aminoquinoline based antiviral drug.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.
Learn how British Pharmacopoeia (BP) sets the standard by offering quality British Pharmacopoeia Chemical Reference Substances (BPCRS).

Packaging

Unit quantity: 25 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Hydroxychloroquine Sulfate
British Pharmacopeia, 2021
British Pharmacopoeia, 44(12), 1000-1004 (2021)
Seminars in Arthritis and Rheumatism, 43(2), 264-272 (2013)
QUALITY BY DESIGN IN THE DEVELOPMENT AND VALIDATION OF ANALYTICAL METHOD BY ULTRAVIOLET-VISIBLE SPECTROPHOTOMETRY FOR QUANTIFICATION OF HYDROXYCHLOROQUINE SULFATE
Ferraz LRM, et al.
International Journal of Pharmaceutical Sciences and Research, 5(11), 4666-4666 (2014)
Development of a novel ion-pairing HPLC-FL method for the separation and quantification of hydroxychloroquine and its metabolites in whole blood
Charlier B,et al.
Biomedical Chromatography, 32(8), e4258-e4258 (2018)
A rapid and reliable method for the quantitation of hydroxychloroquine in serum using turbulent flow liquid chromatography-tandem mass spectrometry
Fuzery AK, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 421 (2013)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service