58358
SUPELCOSIL™ LC-18-DB (5 µm) HPLC Columns
L × I.D. 25 cm × 10 mm, HPLC Column
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About This Item
UNSPSC Code:
41115700
eCl@ss:
32110501
L × i.d.:
25 cm × 10 mm
Particle size:
5 μm
Matrix active group:
C18 (octadecyl) phase
Pore size:
120 Å
Matrix:
silica gel, spherical particle platform
Product Name
SUPELCOSIL™ LC-18-DB HPLC Column, 5 μm particle size, L × I.D. 25 cm × 10 mm
agency
suitable for USP L1
feature
endcapped
manufacturer/tradename
SUPELCOSIL™
extent of labeling
11.0% Carbon loading
parameter
0-70 °C temperature, 400 bar pressure (5801 psi)
technique(s)
HPLC: suitable
L × I.D.
25 cm × 10 mm
surface area
170 m2/g
surface coverage
surface coverage 3.1 μmol/m2
matrix
silica gel, spherical particle platform
matrix active group
C18 (octadecyl) phase
particle size
5 μm
pore size
120 Å
application(s)
food and beverages
separation technique
reversed phase
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General description
SUPELCOSIL LC-DB phases are specially deactivated for basic compounds. These columns provide shorter retention, better peak shape, and higher efficiency for organic bases than can be obtained on other Type A silica reversed-phase columns.
Application
SUPELCOSIL LC-18-DB HPLC Column has been used for the separation of:
- Analytes of pharmaceutical relevance during their analysis using LC in conjunction with principal component analysis (PCA).
- Uracil in aqueous solutions during its separation by reversed phase high performance liquid chromatography equipped with ultraviolet-visible (UV-Vis) detection.
Legal Information
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
Regulatory Information
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Journal of pharmaceutical and biomedical analysis, 24(5-6), 913-920 (2001-03-15)
RGH-1756 (1-(2-methoxy-phenyl)-4-(4-[4-(6-imidazo[2,1-b]-thiazolyl)-phenoxy]-butyl)-piperazine dimethansulphonate) is a novel atypical antipsychotic candidate of Gedeon Richter Ltd. A new HPLC method has been developed and validated for the quantitative determination of RGH-1756 in dog and rat plasma. The compound and the internal standard are
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A HPLC-UV determination of loratadine in human plasma is presented. After simple liquid-liquid extraction with 2-methylbutane-hexane (2:1) and evaporation of organic phase the compounds were re-dissolved in 0.01 M HCl, evaporated again and finally separated on a Supelcosil LC-18-DB column.
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