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Key Documents

Safety Information

WH0001129M1

Sigma-Aldrich

Monoclonal Anti-CHRM2 antibody produced in mouse

clone 4B5, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-FLJ43243, Anti-HM2, Anti-MGC120006, Anti-MGC120007, Anti-cholinergic receptor, muscarinic 2

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1 ML
CN¥1,763.72

CN¥1,763.72

Estimated to ship onApril 27, 2025Details

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1 ML
CN¥1,763.72

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

CN¥1,763.72

Estimated to ship onApril 27, 2025Details

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

4B5, monoclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

indirect ELISA: suitable
western blot: 1-5 μg/mL

isotype

IgG2aκ

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Show Differences

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This Item
SML1147SML0891SML2779
ML-SA1 ≥95% (HPLC)

SML0627

ML-SA1

IQ-1 ≥95% (HPLC)

SML1147

IQ-1

L-152,804 ≥98% (HPLC)

SML0891

L-152,804

Tanaproget ≥98% (HPLC)

SML2779

Tanaproget

assay

≥95% (HPLC)

assay

≥95% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

powder

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

100

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

solubility

DMSO: 5 mg/mL, clear (warmed)

solubility

DMSO: 10 mg/mL, clear

solubility

DMSO: 5 mg/mL, clear (warmed)

solubility

DMSO: 2 mg/mL, clear

color

white to beige

color

yellow to orange

color

white to beige

color

white to beige

General description

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. (provided by RefSeq)

Immunogen

CHRM2 (AAI06743.1, 251 a.a. ~ 350 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
SDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSS

Physical form

Solution in phosphate buffered saline, pH 7.4

Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services

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Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

常规特殊物品

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    Certificates of Analysis (COA)

    Lot/Batch Number
    07135-4B5

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